Evidence map›Paper›PMID 36835128›Full record

ArticleInternational journal of molecular sciences2023

Impairment of Endogenous Synthesis of Omega-3 DHA Exacerbates T-Cell Inflammatory Responses.

Emanuela Talamonti, Anders Jacobsson, Valerio Chiurchiù

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Emanuela TalamontiDepartment of Biochemistry and Biophysics, Stockholm University, 114 Stockholm, Sweden.
Anders JacobssonDepartment of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, 114 Stockholm, Sweden.
Valerio ChiurchiùInstitute of Translational Pharmacology, National Research Council, 00133 Rome, Italy.
Stockholm University · SENational Research Council · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Omega-3 (ω-3) polyunsaturated fatty acids, including docosahexaenoic acid (DHA), are involved in numerous biological processes and have a range of health benefits. DHA is obtained through the action of elongases (ELOVLs) and desaturases, among which Elovl2 is the key enzyme involved in its synthesis, and can be further metabolized into several mediators that regulate the resolution of inflammation. Our group has recently reported that ELOVL2 deficient mice (Elovl2

Indexed as

Docosahexaenoic AcidsInflammationAnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCytokinesFatty Acid ElongasesFatty Acids, Omega-3MiceCytokinesDocosahexaenoic AcidsFatty Acid ElongasesFatty Acids, Omega-3dendritic cellsDHAelongasefatty acidsomega-3T lymphocytes

Identifiers

PMID36835128
PMCPMC9966148
OpenAlexW4320492649

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.