Evidence map›Paper›PMID 36835624›Full record

ArticleInternational journal of molecular sciences2023

Long-Term

Anixa Muiños-Bühl, Roman Rombo, Karen K Ling, Eleonora Zilio, Frank Rigo, C Frank Bennett, Brunhilde Wirth

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Genetic therapies for neurological diseases.Pharmacological reviews · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. In Search of Spinal Muscular Atrophy Disease Modifiers.International journal of molecular sciences · 2024
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Anixa Muiños-BühlInstitute of Human Genetics, University of Cologne, 50931 Cologne, Germany.ORCID 0000-0002-8334-6802
Roman RomboInstitute of Human Genetics, University of Cologne, 50931 Cologne, Germany.
Karen K LingIONIS Pharmaceuticals, Carlsbad, CA 92010, USA.
Eleonora ZilioInstitute of Human Genetics, University of Cologne, 50931 Cologne, Germany.ORCID 0000-0003-4356-7675
Frank RigoIONIS Pharmaceuticals, Carlsbad, CA 92010, USA.
C Frank BennettIONIS Pharmaceuticals, Carlsbad, CA 92010, USA.
Brunhilde WirthInstitute of Human Genetics, University of Cologne, 50931 Cologne, Germany.ORCID 0000-0003-4051-5191
University of Cologne · DEIonis Pharmaceuticals (United States) · US

Funding

Center for Molecular Medicine Cologne C18Deutsche Forschungsgemeinschaft GRK1960 (project ID 233886668)]Deutsche Forschungsgemeinschaft SFB1451 (project 431549029 - A01)Deutsche Forschungsgemeinschaft Wi 945/17-1 (project 398410809)European Union Horizon 2020 Marie Skłodowska-Curie (project 956185; SMABEYOND)
6 · The paper itself

Abstract

For SMA patients with only two

Indexed as

Induced Pluripotent Stem CellsMuscular Atrophy, SpinalAnimalsDisease Models, AnimalHumansMiceMotor NeuronsNeurocalcinOligonucleotidesSurvival of Motor Neuron 1 ProteinNCALD protein, humanNcald protein, mouseNeurocalcinOligonucleotidesSurvival of Motor Neuron 1 Proteinantisense oligonucleotidegenetic modifierhiPSCsNCALDneuromuscular disorderSMASMN2therapy

Identifiers

PMID36835624
PMCPMC9961752
OpenAlexW4321373785

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.