Evidence map›Paper›PMID 36836605›Full record

ArticleJournal of personalized medicine2023

Cystatin-c May Indicate Subclinical Renal Involvement, While Orosomucoid Is Associated with Fatigue in Patients with Long-COVID Syndrome.

Laszlo Zavori, Tihamer Molnar, Reka Varnai, Andrea Kanizsai, Lajos Nagy, Bence Vadkerti, Balazs Szirmay, Attila Schwarcz, Peter Csecsei

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Laszlo ZavoriSalisbury NHS Foundation Trust, Salisbury SP2 8BJ, UK.ORCID 0000-0002-1715-4167
Tihamer MolnarDepartment of Anaesthesiology and Intensive Care, Medical School, University of Pecs, 7624 Pecs, Hungary.ORCID 0000-0002-6149-9787
Reka VarnaiDepartment of Primary Health Care, Medical School, University of Pecs, 7624 Pecs, Hungary.ORCID 0000-0001-8440-3955
Andrea KanizsaiDepartment of Dentistry, Medical School, Pecs, University of Pecs, 7624 Pecs, Hungary.
Lajos NagyDepartment of Applied Chemistry, University of Debrecen, 4032 Debrecen, Hungary.
Bence VadkertiDepartment of Applied Chemistry, University of Debrecen, 4032 Debrecen, Hungary.
Balazs SzirmayDepartment of Laboratory Medicine, Medical School, University of Pecs, 7624 Pecs, Hungary.
Attila SchwarczDepartment of Neurosurgery, Medical School, University of Pecs, 7624 Pecs, Hungary.
Peter CsecseiDepartment of Neurosurgery, Medical School, University of Pecs, 7624 Pecs, Hungary.ORCID 0000-0002-4982-2481
University of Pecs · HUUniversity of Debrecen · HUSalisbury NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-COVID syndrome is associated with high healthcare costs, but its pathophysiology is not yet fully understood. Inflammation, renal impairment or disturbance of the NO system emerge as potential pathogenetic factors. We aimed to investigate the relationship between symptoms of long-COVID syndrome and serum levels of cystatin-c (CYSC), orosomucoid (ORM), l-arginine, symmetric dimethylarginine (SDMA) and asymmetric dimethylarginine (ADMA). A total of 114 patients suffering from long-COVID syndrome were included in this observational cohort study. We found that serum CYSC was independently associated with the anti-spike immunoglobulin (S-Ig) serum level (OR: 5.377, 95% CI: 1.822-12.361;

Indexed as

cystatin-cfatiguel-argininelong-COVID syndromeorosomucoidrenal functionsymmetric dimethylarginine

Identifiers

PMID36836605
PMCPMC9958557
OpenAlexW4321373590

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.