Evidence mapPaperPMID 36836664Full record

ArticleLife (Basel, Switzerland)2023

RETRACTED: Secukinumab and Black Garlic Downregulate OPG/RANK/RANKL Axis and Devitalize Myocardial Interstitial Fibrosis Induced by Sunitinib in Experimental Rats.

Hoda E Mohamad, Mervat E Asker, Mohamed A Shaheen, Nourhan M Baraka, Omer I Fantoukh, Abdulaziz Alqahtani, Alaa E Salama, Yasmin K Mahmoud

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The role of IL-17 family cytokines in cardiac fibrosis.Frontiers in cardiovascular medicine · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Hoda E MohamadDepartment of Biochemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Mervat E AskerDepartment of Biochemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Mohamed A ShaheenDepartment of Histology & Cell Biology, Faculty of Medicine, Zagazig University, Zagazig 44519, Egypt.
Nourhan M BarakaDepartment of Biochemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Omer I FantoukhDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-0262-7101
Abdulaziz AlqahtaniDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Alaa E SalamaDepartment of Cardiology, Faculty of Medicine, Zagazig University, Zagazig 44519, Egypt.
Yasmin K MahmoudDepartment of Biochemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Zagazig University · EGKing Saud University · SA

Funding

King Saud University Researchers Supporting Project number (RSP2022R430)
6 · The paper itself

Abstract

Sunitinib has been associated with several cardiotoxic effects such as cardiac fibrosis. The present study was designed to explore the role of interleukin (IL)-17 in sunitinib-induced myocardial fibrosis (MF) in rats and whether its neutralization and/or administration of black garlic (BG), a form of fermented raw garlic (

Indexed as

black garlicIL-17interstitial myocardial fibrosisOPG/RANK/RANKLsecukinumabsunitinib

Identifiers

PMID36836664
PMCPMC9962443
OpenAlexW4317738893

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.