Evidence map›Paper›PMID 36836894›Full record

ReviewLife (Basel, Switzerland)2023

Lithium: A Promising Anticancer Agent.

Edgar Yebrán Villegas-Vázquez, Laura Itzel Quintas-Granados, Hernán Cortés, Manuel González-Del Carmen, Gerardo Leyva-Gómez, Miguel Rodríguez-Morales, Lilia Patricia Bustamante-Montes, Daniela Silva-Adaya, Carlos Pérez-Plasencia, Nadia Jacobo-Herrera and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. The multiple roles of autophagy in uveal melanoma and the microenvironment.Journal of cancer research and clinical oncology · 2024
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. The Future of Oncology in Psychiatric Medications.Journal of clinical medicine · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. Poly-Unsaturated Fatty Acids (PUFAs) fromJournal of fungi (Basel, Switzerland) · 2024
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

Edgar Yebrán Villegas-VázquezUnidad Multidisciplinaria de Investigación Experimental Zaragoza, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Ciudad de México 09230, Mexico.
Laura Itzel Quintas-GranadosUnidad de Estudios Superiores Tultitlán, Universidad Mexiquense del Bicentenario, Ocoyoacac 54910, Mexico.ORCID 0000-0002-8622-2004
Hernán CortésLaboratorio de Medicina Genómica, Departamento de Genómica, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Ciudad de México 14389, Mexico.ORCID 0000-0002-6147-4109
Manuel González-Del CarmenFacultad de Medicina, Universidad Veracruzana, Ciudad Mendoza 94740, Mexico.
Gerardo Leyva-GómezDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.ORCID 0000-0002-7940-1100
Miguel Rodríguez-MoralesLicenciatura en Médico Cirujano, Facultad de Ciencias de la Salud Universidad Anáhuac Norte, Academia de Genética Médica, Naucalpan de Juárez 52786, Mexico.
Lilia Patricia Bustamante-MontesFacultad de Medicina, Universidad Autónoma del Estado de México, Toluca de Lerdo 50180, Mexico.
Daniela Silva-AdayaLaboratorio Experimental de Enfermedades Neurodegenerativas, Instituto Nacional de Neurología y Neurocirugía, Ciudad de México 14269, Mexico.ORCID 0000-0002-4679-5182
Carlos Pérez-PlasenciaLaboratorio de Genómica, Instituto Nacional de Cancerología (INCan), Ciudad de México 14080, Mexico.ORCID 0000-0002-8593-8211
Nadia Jacobo-HerreraUnidad de Bioquímica, Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubirán (INCMNSZ), Ciudad de México 14080, Mexico.ORCID 0000-0002-1026-3774
Octavio Daniel Reyes-HernándezLaboratorio de Biología Molecular del Cáncer, Unidad Multidisciplinaria de Investigación Experimental Zaragoza, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Ciudad de México 09230, Mexico.ORCID 0000-0002-2767-4799
Gabriela Figueroa-GonzálezLaboratorio de Farmacogenética, Unidad Multidisciplinaria de Investigación Experimental Zaragoza, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Ciudad de México 09230, Mexico.ORCID 0000-0001-8169-4478
Universidad Nacional Autónoma de México · MXAutonomous University of Tlaxcala · MXEl Colegio Mexiquense · MXInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXInstituto Nacional de Neurología y Neurocirugía · MXInstituto Nacional de Rehabilitación · MXUniversidad Anáhuac · MXUniversidad Autónoma del Estado de México · MXUniversidad Veracruzana · MX

Funding

National Autonomous University of Mexico PAPIIT - IA208422
6 · The paper itself

Abstract

Lithium is a therapeutic cation used to treat bipolar disorders but also has some important features as an anti-cancer agent. In this review, we provide a general overview of lithium, from its transport into cells, to its innovative administration forms, and based on genomic, transcriptomic, and proteomic data. Lithium formulations such as lithium acetoacetate (LiAcAc), lithium chloride (LiCl), lithium citrate (Li

Indexed as

anti-cancer effectsapoptosisautophagycancerlithiumnano-delivery

Identifiers

PMID36836894
PMCPMC9966411
OpenAlexW4320918003

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.