Evidence mapPaperPMID 36836902Full record

ArticleLife (Basel, Switzerland)2023

Right Ventricular Morphology and Function after Exercise Training in People with Systemic Sclerosis: A Randomized Controlled Pilot Study.

Maria Anifanti, Andriana Teloudi, Alexandros Mitropoulos, Niki Syrakou, Eleni Pagkopoulou, Eva Triantafyllidou, Carina Boström, Louise Pyndt Diederichsen, Giovanna Cuomo, Theodoros Dimitroulas and 2 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 5 countries.

Maria AnifantiLaboratory of Sports Medicine, Department of Physical Education and Sports Science, Aristotle University of Thessaloniki, 57001 Thessaloniki, Greece.
Andriana TeloudiLaboratory of Sports Medicine, Department of Physical Education and Sports Science, Aristotle University of Thessaloniki, 57001 Thessaloniki, Greece.ORCID 0000-0003-2751-8451
Alexandros MitropoulosLifestyle, Exercise and Nutrition Improvement (LENI) Research Group, Department of Nursing and Midwifery, Sheffield Hallam University, Sheffield S10 2BP, UK.
Niki SyrakouLaboratory of Sports Medicine, Department of Physical Education and Sports Science, Aristotle University of Thessaloniki, 57001 Thessaloniki, Greece.
Eleni Pagkopoulou4th Department of Internal Medicine, School of Medicine, Hipokration Hospital, Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece.ORCID 0000-0002-5755-1538
Eva Triantafyllidou4th Department of Internal Medicine, School of Medicine, Hipokration Hospital, Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece.
Carina BoströmDepartment of Neurobiology, Care Sciences and Society, Karolinska Institutet, SE-104 35 Stockholm, Sweden.ORCID 0000-0002-2506-687X
Louise Pyndt DiederichsenCopenhagen Research Centre for Autoimmune Connective Tissue Diseases, Copenhagen University, Rigshospitalet, DK-1165 Copenhagen, Denmark.
Giovanna CuomoDepartment of Precision Medicine, University of Campania L. Vanvitelli, 80138 Naples, Italy.ORCID 0000-0002-4292-3589
Theodoros Dimitroulas4th Department of Internal Medicine, School of Medicine, Hipokration Hospital, Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece.ORCID 0000-0002-0364-1642
Markos KlonizakisLifestyle, Exercise and Nutrition Improvement (LENI) Research Group, Department of Nursing and Midwifery, Sheffield Hallam University, Sheffield S10 2BP, UK.
Evangelia KouidiLaboratory of Sports Medicine, Department of Physical Education and Sports Science, Aristotle University of Thessaloniki, 57001 Thessaloniki, Greece.ORCID 0000-0002-5023-2542
Aristotle University of Thessaloniki · GRSheffield Hallam University · GBCopenhagen University Hospital · DKKarolinska Institutet · SEUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVascular dysfunction and its concomitant multi-organ involvement, including cardiac involvement, affects prognosis in systemic sclerosis (SSc) patients. Regular exercise has demonstrated to be able to improve vascular function in SSc. However, the effects of an exercise program on the heart and specifically in right ventricular (RV) morphology and function in SSc have yet to be explored. The study aimed to examine whether a 3-month combined exercise program can affect RV morphology and function in SSc patients.

methodsTwenty-eight SSc patients were randomly allocated to either the exercise training (ET) or the control (CON) group. Baseline and follow-up assessments consisted of a cardiopulmonary exercise test along with both a conventional and a two-dimensional speckle tracking echocardiography (2DSTE) focused on RV morphology and function. Following the baseline assessments, Group ET participated in a supervised combined exercise program for 12 weeks, while group CON received their usual care.

resultsThe ET group demonstrated increases in peak oxygen consumption by 25.1% (

conclusionsCombined exercise improved cardiorespiratory efficiency and indices of RV systolic function, as assessed by the 2DSTE, in SSc patients.

Indexed as

cardiopulmonary exercise testingechocardiographyexercise trainingright ventricular functionsystemic sclerosis

Identifiers

PMID36836902
PMCPMC9958927
OpenAlexW4321104675

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.