Evidence map›Paper›PMID 36836946›Full record

ReviewLife (Basel, Switzerland)2023

Addressing Spaceflight Biology through the Lens of a Histologist-Embryologist.

Paschalis Theotokis, Maria Eleni Manthou, Theodora-Eleftheria Deftereou, Dimosthenis Miliaras, Soultana Meditskou

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Paschalis TheotokisLaboratory of Histology and Embryology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0001-8607-6695
Maria Eleni ManthouLaboratory of Histology and Embryology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0001-7075-878X
Theodora-Eleftheria DeftereouLaboratory of Histology and Embryology, Democritus University of Thrace, 69100 Alexandroupolis, Greece.
Dimosthenis MiliarasLaboratory of Histology and Embryology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-3562-7108
Soultana MeditskouLaboratory of Histology and Embryology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Aristotle University of Thessaloniki · GRDemocritus University of Thrace · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Embryogenesis and fetal development are highly delicate and error-prone processes in their core physiology, let alone if stress-associated factors and conditions are involved. Space radiation and altered gravity are factors that could radically affect fertility and pregnancy and compromise a physiological organogenesis. Unfortunately, there is a dearth of information examining the effects of cosmic exposures on reproductive and proliferating outcomes with regard to mammalian embryonic development. However, explicit attention has been given to investigations exploring discrete structures and neural networks such as the vestibular system, an entity that is viewed as the sixth sense and organically controls gravity beginning with the prenatal period. The role of the gut microbiome, a newly acknowledged field of research in the space community, is also being challenged to be added in forthcoming experimental protocols. This review discusses the data that have surfaced from simulations or actual space expeditions and addresses developmental adaptations at the histological level induced by an extraterrestrial milieu.

Indexed as

brain plasticityembryo developmentgut microbiomemicrogravityorganogenesisradiationspace travelvestibular system

Identifiers

PMID36836946
PMCPMC9965490
OpenAlexW4321459616

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.