Evidence map›Paper›PMID 36837853›Full record

ArticleMetabolites2023

Placental Metabolomics of Fetal Growth Restriction.

Jacopo Troisi, Steven J K Symes, Martina Lombardi, Pierpaolo Cavallo, Angelo Colucci, Giovanni Scala, David C Adair, Maurizio Guida, Sean M Richards

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jacopo TroisiDepartment of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, SA, Italy.ORCID 0000-0003-2962-7379
Steven J K SymesDepartment of Chemistry and Physics, University of Tennessee at Chattanooga, 615 McCallie Ave., Chattanooga, TN 37403, USA.ORCID 0000-0002-5741-439X
Martina LombardiTheoreo srl, Via degli Ulivi 3, 84090 Montecorvino Pugliano, SA, Italy.ORCID 0000-0003-4453-6627
Pierpaolo CavalloDepartment of Physics, University of Salerno, 84084 Fisciano, SA, Italy.ORCID 0000-0003-3111-5241
Angelo ColucciDepartment of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, SA, Italy.ORCID 0000-0001-7152-7254
Giovanni ScalaTheoreo srl, Via degli Ulivi 3, 84090 Montecorvino Pugliano, SA, Italy.
David C AdairDepartment of Obstetrics and Gynecology, Section on Maternal-Fetal Medicine, University of Tennessee College of Medicine, 979 East Third Street, Suite C-720, Chattanooga, TN 37403, USA.ORCID 0000-0002-5422-227X
Maurizio GuidaTheoreo srl, Via degli Ulivi 3, 84090 Montecorvino Pugliano, SA, Italy.
Sean M RichardsDepartment of Obstetrics and Gynecology, Section on Maternal-Fetal Medicine, University of Tennessee College of Medicine, 979 East Third Street, Suite C-720, Chattanooga, TN 37403, USA.
University of Salerno · ITUniversity of Tennessee at Chattanooga · USUniversity of Naples Federico II · IT

Funding

HRSA HHS 1H1SMC10654-01-00
6 · The paper itself

Abstract

Fetal growth restriction is an obstetrical pathological condition that causes high neonatal mortality and morbidity. The mechanisms of its onset are not completely understood. Metabolites were extracted from 493 placentas from non-complicated pregnancies in Hamilton Country, TN (USA), and analyzed by gas chromatography-mass spectrometry (GC-MS). Newborns were classified according to raw fetal weight (low birth weight (LBW; <2500 g) and non-low birth weight (Non-LBW; >2500 g)), and according to the calculated birth weight centile as it relates to gestational age (small for gestational age (SGA), large for gestational age (LGA), and adequate for gestational age (AGA)). Mothers of LBW infants had a lower pre-pregnancy weight (66.2 ± 17.9 kg vs. 73.4 ± 21.3 kg,

Indexed as

fetal growth restrictionlow birth weightmetabolomicssmall for gestational age

Identifiers

PMID36837853
PMCPMC9959525
OpenAlexW4319317157

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.