Evidence map›Paper›PMID 36838091›Full record

ReviewMicromachines2023

Exhaled Biomarkers for Point-of-Care Diagnosis: Recent Advances and New Challenges in Breathomics.

Helga Kiss, Zoltán Örlős, Áron Gellért, Zsolt Megyesfalvi, Angéla Mikáczó, Anna Sárközi, Attila Vaskó, Zsuzsanna Miklós, Ildikó Horváth

Open access · goldAbstract readReview
In one paragraph

Review in Micromachines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Low-Temperature Ammonia Sensing Using Sulfurized WSSensors (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. A translational view of airway epithelial dysfunction in COPD.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  8. Article
  9. Observational
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Helga KissNational Koranyi Institute for Pulmonology, Koranyi F Street 1, 1121 Budapest, Hungary.
Zoltán ÖrlősNational Koranyi Institute for Pulmonology, Koranyi F Street 1, 1121 Budapest, Hungary.
Áron GellértNational Koranyi Institute for Pulmonology, Koranyi F Street 1, 1121 Budapest, Hungary.
Zsolt MegyesfalviNational Koranyi Institute for Pulmonology, Koranyi F Street 1, 1121 Budapest, Hungary.
Angéla MikáczóDepartment of Pulmonology, University of Debrecen, Nagyerdei krt 98, 4032 Debrecen, Hungary.
Anna SárköziDepartment of Pulmonology, University of Debrecen, Nagyerdei krt 98, 4032 Debrecen, Hungary.
Attila VaskóDepartment of Pulmonology, University of Debrecen, Nagyerdei krt 98, 4032 Debrecen, Hungary.
Zsuzsanna MiklósNational Koranyi Institute for Pulmonology, Koranyi F Street 1, 1121 Budapest, Hungary.ORCID 0000-0001-8577-4475
Ildikó HorváthNational Koranyi Institute for Pulmonology, Koranyi F Street 1, 1121 Budapest, Hungary.
Országos Korányi Tbc és Pulmonológiai Intézet · HUUniversity of Debrecen · HU

Funding

Hungarian National Research, Development and Innovation Office OTKA 128666 and OTKA 124343
6 · The paper itself

Abstract

Cancers, chronic diseases and respiratory infections are major causes of mortality and present diagnostic and therapeutic challenges for health care. There is an unmet medical need for non-invasive, easy-to-use biomarkers for the early diagnosis, phenotyping, predicting and monitoring of the therapeutic responses of these disorders. Exhaled breath sampling is an attractive choice that has gained attention in recent years. Exhaled nitric oxide measurement used as a predictive biomarker of the response to anti-eosinophil therapy in severe asthma has paved the way for other exhaled breath biomarkers. Advances in laser and nanosensor technologies and spectrometry together with widespread use of algorithms and artificial intelligence have facilitated research on volatile organic compounds and artificial olfaction systems to develop new exhaled biomarkers. We aim to provide an overview of the recent advances in and challenges of exhaled biomarker measurements with an emphasis on the applicability of their measurement as a non-invasive, point-of-care diagnostic and monitoring tool.

Indexed as

artificial olfaction systembiosensorsbreathomicsCOVID-19electronic noseexhaled carbon monoxideexhaled hydrogen sulfideexhaled nitric oxidevolatile organic compounds

Identifiers

PMID36838091
PMCPMC9964519
OpenAlexW4319317096

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.