Evidence map›Paper›PMID 36839082›Full record

ArticleNanomaterials (Basel, Switzerland)2023

Oxidized-Multiwalled Carbon Nanotubes as Non-Toxic Nanocarriers for Hydroxytyrosol Delivery in Cells.

Panagiota Zygouri, Antrea M Athinodorou, Konstantinos Spyrou, Yannis V Simos, Mohammed Subrati, Georgios Asimakopoulos, Konstantinos C Vasilopoulos, Patra Vezyraki, Dimitrios Peschos, Konstantinos Tsamis and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Panagiota ZygouriDepartment of Materials Science and Engineering, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0002-7137-6633
Antrea M AthinodorouDepartment of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0002-5060-4588
Konstantinos SpyrouDepartment of Materials Science and Engineering, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0002-2032-8439
Yannis V SimosNanomedicine and Nanobiotechnology Research Group, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0003-1764-8906
Mohammed SubratiDepartment of Materials Science and Engineering, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0002-9349-7073
Georgios AsimakopoulosDepartment of Materials Science and Engineering, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0002-1384-7396
Konstantinos C VasilopoulosDepartment of Materials Science and Engineering, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0002-4263-0524
Patra VezyrakiDepartment of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece.
Dimitrios PeschosNanomedicine and Nanobiotechnology Research Group, University of Ioannina, 45110 Ioannina, Greece.
Konstantinos TsamisNanomedicine and Nanobiotechnology Research Group, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0002-7032-1630
Dimitrios P GournisDepartment of Materials Science and Engineering, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0003-4256-8190
University of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbon nanotubes (CNTs) possess excellent physicochemical and structural properties alongside their nano dimensions, constituting a medical platform for the delivery of different therapeutic molecules and drug systems. Hydroxytyrosol (HT) is a molecule with potent antioxidant properties that, however, is rapidly metabolized in the organism. HT immobilized on functionalized CNTs could improve its oral absorption and protect it against rapid degradation and elimination. This study investigated the effects of cellular oxidized multiwall carbon nanotubes (oxMWCNTs) as biocompatible carriers of HT. The oxidation of MWCNTs via H

Indexed as

antioxidantcytotoxicityhydroxytyrosolmulti-walled carbon nanotubesoxidation

Identifiers

PMID36839082
PMCPMC9965370
OpenAlexW4320498073

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.