Evidence map›Paper›PMID 36839167›Full record

Trial reportNutrients2023

The Effect of Watermelon Juice Supplementation on Heart Rate Variability and Metabolic Response during an Oral Glucose Challenge: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial.

Rachel Matthews, Kate S Early, Cullen M Vincellette, Jack Losso, Guillaume Spielmann, Brian A Irving, Timothy D Allerton

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rachel MatthewsDepartment of Kinesiology, Louisiana State University, Baton Rouge, LA 70803, USA.
Kate S EarlyDepartment of Kinesiology and Health Sciences, Columbus State University, Columbus, GA 39207, USA.ORCID 0000-0002-2714-339X
Cullen M VincelletteDepartment of Kinesiology, Louisiana State University, Baton Rouge, LA 70803, USA.
Jack LossoSchool of Nutrition and Food Sciences, Louisiana State University, Baton Rouge, LA 70803, USA.
Guillaume SpielmannDepartment of Kinesiology, Louisiana State University, Baton Rouge, LA 70803, USA.
Brian A IrvingDepartment of Kinesiology, Louisiana State University, Baton Rouge, LA 70803, USA.ORCID 0000-0002-4131-9523
Timothy D AllertonPennington Biomedical Research Center, Vascular Metabolism Laboratory, Baton Rouge, LA 70808, USA.ORCID 0000-0001-6364-5787
Louisiana State University · USColumbus State University · USPennington Biomedical Research Center · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

Heart rate variability (HRV) provides a simple method to evaluate autonomic function in health and disease. A reduction in HRV may indicate autonomic dysfunction and is strongly associated with aspects of cardiometabolic disease, including hyperglycemia. Reduced nitric oxide (NO) bioavailability is also implicated in the development of cardiometabolic disease and autonomic dysfunction. Watermelons are natural sources of L-arginine and L-citrulline, substrates used for NO synthesis. Watermelon consumption can improve NO bioavailability. We conducted a randomized, double-blind, placebo-controlled crossover trial to test the effects of 2 weeks of daily watermelon juice (WMJ) supplementation on HRV in response to an oral glucose challenge (OGC) in healthy young adults. We also performed indirect calorimetry to assess if our intervention altered the metabolic response to the OGC. WMJ supplementation preserved high-frequency power (HF) (treatment effect,

Indexed as

Cardiovascular DiseasesCitrullusCross-Over StudiesDietary SupplementsDouble-Blind MethodGlucoseHeart RateHumansYoung AdultGlucoseautonomic functionheart rate variabilityhyperglycemiaindirect calorimetryL-arginineL-citrullinemetabolismnitric oxidewatermelon

Identifiers

PMID36839167
PMCPMC9967111
OpenAlexW4319298580

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.