Evidence map›Paper›PMID 36839631›Full record

ArticlePharmaceutics2023

Focal Photocoagulation as an Adjunctive Therapy to Reduce the Burden of Intravitreal Injections in Macula Edema Patients, the LyoMAC2 Study.

Lucas Séjournet, Laurent Kodjikian, Sandra Elbany, Benoit Allignet, Emilie Agard, Mayeul Chaperon, Jérémy Billant, Philippe Denis, Thibaud Mathis, Carole Burillon and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Islets persisting on OCT macular thickness map after intravitreal injections unmask telangiectatic capillaries (TelCaps) in diabetic macular edema.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Lucas SéjournetDepartment of Ophthalmology, Desgenettes Military Hospital, 69003 Lyon, France.
Laurent KodjikianDepartment of Ophthalmology, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France.ORCID 0000-0002-3908-6716
Sandra ElbanyDepartment of Ophthalmology, Hôpital Edouard Herriot, Hospices Civils de Lyon, 69003 Lyon, France.
Benoit AllignetDepartment of Radiation Oncology, Centre Léon Bérard, 28 rue Laennec, 69673 Lyon, France.ORCID 0000-0001-7275-0773
Emilie AgardDepartment of Ophthalmology, Desgenettes Military Hospital, 69003 Lyon, France.ORCID 0000-0001-8273-550X
Mayeul ChaperonDepartment of Ophthalmology, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France.
Jérémy BillantDepartment of Ophthalmology, Desgenettes Military Hospital, 69003 Lyon, France.ORCID 0000-0002-8388-3755
Philippe DenisDepartment of Ophthalmology, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France.
Thibaud MathisDepartment of Ophthalmology, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France.ORCID 0000-0002-1418-1872
Carole BurillonDepartment of Ophthalmology, Hôpital Edouard Herriot, Hospices Civils de Lyon, 69003 Lyon, France.
Corinne DotDepartment of Ophthalmology, Desgenettes Military Hospital, 69003 Lyon, France.ORCID 0000-0003-4398-3978
Hôpital de la Croix-Rousse · FRHôpital d'instruction des Armées Desgenettes · FRHospices Civils de Lyon · FRHIA du Val-de-Grâce à Paris · FRUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess the efficacy of focal photocoagulation of capillary macroaneurysms (CMA) to reduce the burden of intravitreal injections (IVI) in patients with macular edema (ME). MATERIALS AND

methodsRetrospective multicenter study in patients with diabetic ME or ME secondary to retinal vein occlusion (ME-RVO). CMA associated with ME were selectively photocoagulated. Patients were followed for one year after photocoagulation.

results93 eyes of 76 patients were included in this study. At 6 months after the laser (n = 93), there was a significant decrease in mean macular thickness (from 354 µm to 314 µm,

conclusionFocal laser photocoagulation of CMA seems to be effective and safe for reducing the burden of IVI in patients with ME. Their screening during the follow-up should be considered closely.

Indexed as

capillary macroaneurysmsdiabetic macular edemafocal laser photocoagulationmacular edemaretinal vein occlusiontelangiectatic capillaries

Identifiers

PMID36839631
PMCPMC9966640
OpenAlexW4317103281

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.