Evidence map›Paper›PMID 36839651›Full record

ArticlePharmaceutics2023

The Antibiotic Kitasamycin-A Potential Agent for Specific Fibrosis Preventing Therapy after Fistulating Glaucoma Surgery?

Katharina A Sterenczak, Georg Fuellen, Anselm Jünemann, Rudolf F Guthoff, Oliver Stachs, Thomas Stahnke

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Katharina A SterenczakDepartment of Ophthalmology, Rostock University Medical Center, 18057 Rostock, Germany.ORCID 0000-0002-8122-4203
Georg FuellenInstitute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, 18057 Rostock, Germany.
Anselm JünemannDepartment of Ophthalmology, Rostock University Medical Center, 18057 Rostock, Germany.
Rudolf F GuthoffDepartment of Ophthalmology, Rostock University Medical Center, 18057 Rostock, Germany.
Oliver StachsDepartment of Ophthalmology, Rostock University Medical Center, 18057 Rostock, Germany.
Thomas StahnkeDepartment of Ophthalmology, Rostock University Medical Center, 18057 Rostock, Germany.ORCID 0000-0003-2425-7268
University of Rostock · DEInstitute for ImplantTechnology and Biomaterials · DE

Funding

Deutsche Forschungsgemeinschaft KO 5003/1-2Else-Hirschberg FrauenförderplanFederal Ministry of Education and Research Antifibrotix, 03VP06230Federal Ministry of Education and Research RESPONSE "Partnership for Innovation in Implant Technology"
6 · The paper itself

Abstract

One major complication after fistulating glaucoma surgeries are fibroblast-mediated scarring processes and their specific prevention is key in the development of novel pharmaceutical concepts. Within this study a possible antifibrotic potential of kitasamycin (KM) in a transforming growth factor (TGF)-β1-mediated fibroblast model was evaluated

Indexed as

fibrosisglaucoma surgerykitasamycinnovel pharmaceutical conceptsspecific antifibrotic agent

Identifiers

PMID36839651
PMCPMC9960401
OpenAlexW4317425945

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.