Evidence map›Paper›PMID 36840766›Full record

ArticleEuropean radiology2023

Aneurysm wall enhancement, atherosclerotic proteins, and aneurysm size may be related in unruptured intracranial fusiform aneurysms.

Fei Peng, Hao Niu, Xin Feng, Lang Liu, Peng Xu, Hong Zhang, Jigang Chen, Xin Tong, Jiaxiang Xia, Xiaoxin He and 6 more

Abstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Fei Peng *Neurointerventional Center, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100070, China.
Hao Niu *Neurointerventional Center, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100070, China.
Xin FengDepartment of Cerebrovascular Surgery, Engineering Technology Research Center of Education Ministry of China On Diagnosis and Treatment of Cerebrovascular Disease, Neurosurgery Center, Zhujiang Hospital, Southern Medical University, Guangzhou, 510280, Guangdong, China.
Lang LiuDepartment of Neurosurgery, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Peng XuDepartment of Neurosurgery, Hengyang Medical School, The Second Affiliated Hospital, University of South China, Hengyang, Hunan, China.
Hong ZhangOperating Room, Heze Municipal Hospital, Heze, Shandong, China.
Jigang ChenNeurointerventional Center, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100070, China.
Xin TongNeurointerventional Center, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100070, China.
Jiaxiang XiaNeurointerventional Center, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100070, China.
Xiaoxin HeNeurointerventional Center, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100070, China.
Boya XuNeurointerventional Center, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100070, China.
Xuge ChenNeurointerventional Center, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100070, China.
Binbin SuiTiantan Neuroimaging Center of Excellence, China National Clinical Research Center for Neurological Diseases, No. 119, South 4Th Ring West Road, Fengtai District, Beijing, 100070, China.
Yonghong DuanDepartment of Neurosurgery, Hengyang Medical School, The Second Affiliated Hospital, University of South China, Hengyang, Hunan, China.
Xingquan Zhao *Tiantan Neuroimaging Center of Excellence, China National Clinical Research Center for Neurological Diseases, No. 119, South 4Th Ring West Road, Fengtai District, Beijing, 100070, China. zxq@vip.163.com.
Aihua Liu *Neurointerventional Center, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100070, China. liuaihuadoctor@163.com.ORCID http://orcid.org/0000-0002-6391-805X
Capital Medical University · CNUniversity of South China · CNBeijing Tian Tan Hospital · CNCentral South University · CNHeze Municipal Hospital · CNNational Clinical Research Center for Digestive Diseases · CNZhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis cross-sectional study aimed to investigate the associations between aneurysm wall enhancement (AWE), atherosclerotic protein levels, and aneurysm size in unruptured intracranial fusiform aneurysms (IFAs).

methodsPatients with IFAs underwent high-resolution magnetic resonance imaging (HR-MRI) and atherosclerotic protein examinations from May 2015 to December 2021 were collected. A CR

resultsSeventy-one IFAs from 71 patients were included in the study. Multivariate analysis revealed statin use (OR = 0.189, p = 0.026) and apolipoprotein B (Apo-B) level (OR = 6.019, p = 0.026) were the independent predictors of AWE in IFAs. In addition, statin use (OR = 0.813, p = 0.036) and Apo-B level (OR = 1.610, p = 0.003) were also the independent predictors of CR

conclusionsThere may be correlations between AWE, atherosclerotic protein levels, and aneurysm size in patients with IFAs. Apo-B and statin use were independent predictors of AWE in IFAs, which have the potential to be new therapeutic targets for IFAs. KEY POINTS: • There may be correlations between aneurysm wall enhancement, atherosclerotic protein levels in the peripheral blood, and aneurysm size in patients with intracranial fusiform aneurysms. • Apolipoprotein B and statin use were independent predictors of aneurysm wall enhancement in intracranial fusiform aneurysms.

Indexed as

Hydroxymethylglutaryl-CoA Reductase InhibitorsIntracranial AneurysmThrombosisApolipoproteinsCross-Sectional StudiesHumansMagnetic Resonance ImagingApolipoproteinsHydroxymethylglutaryl-CoA Reductase InhibitorsAneurysmApolipoproteins BHydroxymethylglutaryl-CoA reductase inhibitorsMagnetic resonance imaging

Identifiers

PMID36840766
OpenAlexW4321851618

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.