Evidence map›Paper›PMID 36840901›Full record

ArticleClinical and experimental nephrology2023

Depression and health-related quality of life in adolescents and young adults with childhood-onset end-stage kidney disease: a multicenter study in Japan.

Kenichiro Miura, Motoshi Hattori, Masayuki Iwano, Eisuke Inoue, Yoshimitsu Gotoh, Takayuki Okamoto, Kei Nishiyama, Daishi Hirano, Katsuji Nishimura, Ichiei Narita

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Clinical and experimental nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kenichiro MiuraDepartment of Pediatric Nephrology, Tokyo Women's Medical University, 8-1 Kawada-Cho, Shinjuku-Ku, Tokyo, 162-8666, Japan.
Motoshi HattoriDepartment of Pediatric Nephrology, Tokyo Women's Medical University, 8-1 Kawada-Cho, Shinjuku-Ku, Tokyo, 162-8666, Japan. hattori@twmu.ac.jp.ORCID http://orcid.org/0000-0002-4309-8672
Masayuki IwanoDepartment of Nephrology, Faculty of Medical Sciences, University of Fukui, 23-3 Shimoaizuki, Matsuoka, Eiheiji-Cho, Yoshida-Gun, Fukui, 910-1193, Japan.
Eisuke InoueShowa University Research Administration Center, Showa University, 1-5-8 Hatanodai, Shinagawa-Ku, Tokyo, 142-8666, Japan.
Yoshimitsu GotohDepartment of Pediatric Nephrology, Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, 2-9 Myoken-Cho Showa-Ku, Nagoya-Shi, Aichi, 466-8650, Japan.
Takayuki OkamotoDepartment of Pediatrics, Hokkaido University Graduate School of Medicine, Kita 15-Jo Nishi 7-Chome, Kita Ward, Sapporo, Hokkaido, 060-0815, Japan.
Kei NishiyamaDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-0054, Japan.
Daishi HiranoDepartment of Pediatrics, The Jikei University School of Medicine, 3-25-8 Nishi-Shimbashi, Minato-Ku, Tokyo, 105-0003, Japan.
Katsuji NishimuraDepartment of Psychiatry, Tokyo Women's Medical University, 8-1 Kawada-Cho, Shinjuku-Ku, Tokyo, 162-8666, Japan.
Ichiei NaritaDivision of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-Dori, Niigata-Shi, Niigata, 951-8510, Japan.

Funding

Ministry of Health, Labour and Welfare 20FC1045
6 · The paper itself

Abstract

backgroundPatient survival and physical outcomes among children with end-stage kidney disease (ESKD) have significantly improved, and recent research has focused on long-term depression symptoms and health-related quality of life (HRQOL). However, no studies have been conducted among adolescents and young adults with childhood-onset ESKD in Japan.

methodsThis multicenter study included 45 adolescents and young adults aged 16-39 years who developed ESKD at age < 20 years. Depression symptoms were measured using the Beck Depression Inventory (BDI)-II. The Short Form-36 Health Survey (SF-36) was used to assess HRQOL. Factors associated with depression and HRQOL were analyzed.

resultsDepression (BDI-II score ≥ 14) was observed in 13 (29%) patients. Patient's SF-36 physical component summary (PCS) and mental component summary (MCS) scores were comparable with those for the general population. Lower estimated glomerular filtration rate, higher BDI-II scores, and lower body mass index were associated with lower PCS scores. BDI-II scores were negatively correlated with MCS scores. We observed a trend that unemployment was associated with lower MCS scores.

conclusionsDepression is frequently observed among adolescents and young adults with childhood-onset ESKD. Regular screening for psychosocial concerns, maintaining stable graft functions, and achieving optimal nutritional status may contribute to improved well-being among these patients.

Indexed as

Kidney Failure, ChronicQuality of LifeAdolescentAdultChildDepressionHumansJapanNutritional StatusSurveys and QuestionnairesYoung AdultAdolescentsDepressionEnd-stage kidney diseaseHealth-related quality of lifeYoung adults

Identifiers

PMID36840901

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.