Evidence map›Paper›PMID 36843503›Full record

Trial reportClinical obesity2023

The effect of exercise training level on arterial stiffness after clinically significant weight loss.

Damon L Swift, Joshua E McGee, Emily E Grammer, Anna C Huff, Marie C Clunan, Nicole Hursey, Taylor T Brown, Briceida G Osborne, Joseph A Houmard, Robert A Carels and 2 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical obesity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Damon L SwiftDepartment of Kinesiology, East Carolina University, Greenville, North Carolina, USA.ORCID https://orcid.org/0000-0001-6223-6930
Joshua E McGeeDepartment of Kinesiology, East Carolina University, Greenville, North Carolina, USA.
Emily E GrammerDepartment of Kinesiology, East Carolina University, Greenville, North Carolina, USA.
Anna C HuffDepartment of Kinesiology, East Carolina University, Greenville, North Carolina, USA.
Marie C ClunanDepartment of Kinesiology, East Carolina University, Greenville, North Carolina, USA.
Nicole HurseyDepartment of Kinesiology, East Carolina University, Greenville, North Carolina, USA.
Taylor T BrownDepartment of Kinesiology, East Carolina University, Greenville, North Carolina, USA.
Briceida G OsborneECU Health Wellness Center, Greenville, North Carolina, USA.
Joseph A HoumardDepartment of Kinesiology, East Carolina University, Greenville, North Carolina, USA.
Robert A CarelsDepartment of Psychology, East Carolina University, Greenville, North Carolina, USA.
Walter J PoriesDepartment of Surgery, East Carolina University, Greenville, North Carolina, USA.
Laura E MatareseDepartment of Internal Medicine, East Carolina University, Greenville, North Carolina, USA.
East Carolina University · USHeadache Wellness Center · US

Funding

Prescribed Exercise to Reduce Recidivism After Weight LossR56HL132961 · NHLBI · EAST CAROLINA UNIVERSITY · PI SWIFT, DAMON LEO · 2018 to 2018
$736k
NHLBI NIH HHS R56 HL132961NHLBI NIH HHS R56HL132961-01
6 · The paper itself

Abstract

Arterial stiffness is improved by weight loss. However, no data exist on the impact of aerobic exercise levels on arterial stiffness during weight maintenance. Adults who were  overweight or with obesity (N = 39) participated in a 10-week weight loss program. Participants who achieved ≥7% weight loss were randomized to aerobic training at the minimum physical activity guidelines (PA-REC, 550 MET min/week) or weight maintenance guidelines (WM-REC, 970 MET min/week) for 18 additional weeks. Arterial stiffness (carotid-to-femoral pulse wave velocity [cfPWV], augmentation index normalized for 75 beats/min [AIX75]) and blood pressure [aortic and brachial]) were assessed at baseline, the end of the weight loss phase (week 10), and follow-up (week 28). There was a reduction in cfPWV in participants who met the weight loss goal (-0.34 m/s, p = .02) and approached significance for the entire sample (p = .051). Similarly, there were reductions in AIX75, brachial blood pressure, and aortic blood pressure (p < .05) in the full sample. In the weight maintenance phase, no differences were observed between the PA-REC and the WM-REC groups for change in arterial stiffness or blood pressure (p > .05). However, changes in cfPWV were independently associated with changes in LDL (r

Indexed as

Pulse Wave AnalysisVascular StiffnessAdultBlood PressureExerciseHumansWeight Lossarterial stiffnessexerciseobesitypulse wave velocityweight lossweight maintenance

Identifiers

PMID36843503
PMCPMC11036368
OpenAlexW4322496056

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.