Evidence map›Paper›PMID 36847008›Full record

ArticleJournal of Alzheimer's disease : JAD2023

Relationship Between Cognitive Performance, Physical Activity, and Socio-Demographic/Individual Characteristics Among Aging Americans.

Imtiaz Masfique Dowllah, Juan Lopez-Alvarenga, Gladys E Maestre, Ulku Karabulut, Michael Lehker, Murat Karabulut

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Imtiaz Masfique DowllahDepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, USA.
Juan Lopez-AlvarengaDepartment of Neuroscience, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.
Gladys E MaestreDepartment of Neuroscience, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.
Ulku KarabulutDepartment of Health and Human Performance, University of Texas Rio Grande Valley, Brownsville, TX, USA.
Michael LehkerDepartment of Health and Biomedical Sciences, University of Texas Rio Grande Valley, Brownsville, TX, USA.
Murat KarabulutDepartment of Health and Human Performance, University of Texas Rio Grande Valley, Brownsville, TX, USA.
The University of Texas Rio Grande Valley · USUniversity of Florida · US

Funding

South Texas Alzheimer's Disease Research CenterP30AG066546 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Mohamad Habes · 2021 to 2026
$24.0M
Cognitively Healthy Nonagenarians in the Cross Cohort Collaboration (CCC)RF1AG059421 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SESHADRI, SUDHA · 2018 to 2018
$6.1M
Rio Grande Valley Alzheimer's Resource Center for Minority Aging Research: Partnerships for ProgressP30AG059305 · NIA · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI Eron Grant Manusov · 2018 to 2026
$5.8M
Integration of Socio-Spatial Data for Neighborhoods with Multi-omic profiles to Identify and Mitigate Factors Affecting Risk of ALzheimer's DiseaseDP1AG069870 · NIA · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI MAESTRE, GLADYS E. · 2020 to 2024
$3.6M
NIA NIH HHS DP1 AG069870NIA NIH HHS P30 AG059305NIA NIH HHS P30 AG066546NIA NIH HHS RF1 AG059421
6 · The paper itself

Abstract

backgroundPhysical activity (PA) has emerged as a promising approach to delay Alzheimer's disease and related dementias, but the optimal intensity of PA to improve cognitive health remains unknown.

objectiveTo evaluate the association between duration and intensity of PA and cognitive domains (executive function, processing speed, and memory) in aging Americans.

methodsLinear regressions in hierarchical blocks for variable adjustment and the size of effect (η2) were analyzed by using the data of 2,377 adults (age = 69.3±6.7 years) from the NHANES 2011-2014.

resultsParticipants with 3-6 h/week of vigorous- and > 1 h/week of moderate-intensity PA scored significantly higher in executive function and processing speed domains of cognition compared to inactive peers (η2 = 0.005 & 0.007 respectively, p < 0.05). After adjustment, the beneficial effects of 1-3 h /week of vigorous-intensity PA became trivial for delayed recall memory domain test scores (β= 0.33; 95% CI: -0.01,0.67; η2 = 0.002; p = 0.56). There was no linear dose-response relationship between the cognitive test scores and weekly moderate-intensity of PA. Interestingly, higher handgrip strength and higher late-life body mass index were associated with a higher performance across all cognitive domains.

conclusionOur study supports habitual PA with superior cognition health in some but not all domains among older adults. Furthermore, increased muscle strength and higher late-life adiposity may also impact cognition.

Indexed as

AgingHand StrengthAgedCognitionDemographyExerciseHumansNutrition SurveysPhysical Functional PerformanceAlzheimer’s diseasebody mass indexcognitive functionexecutive functionhandgrip strengthphysical activity

Identifiers

PMID36847008
PMCPMC10693475
OpenAlexW4321791246

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.