Evidence map›Paper›PMID 36848551›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Giovanni Bussotti, Blaise Li, Pascale Pescher, Barbora Vojtkova, Isabelle Louradour, Katerina Pruzinova, Jovana Sadlova, Petr Volf, Gerald F Späth

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Giovanni BussottiInstitut Pasteur, Université Paris Cité, Bioinformatics and Biostatistics Hub, F-75015 Paris, France.ORCID 0000-0002-4078-7413
Blaise LiInstitut Pasteur, Université Paris Cité, Bioinformatics and Biostatistics Hub, F-75015 Paris, France.ORCID 0000-0003-3080-1899
Pascale PescherInstitut Pasteur, Université Paris Cité, INSERM U1201, Unité de Parasitologie moléculaire et Signalisation, F-75015 Paris, France.ORCID 0000-0003-2796-7855
Barbora VojtkovaDepartment of Parasitology, Faculty of Science, Charles University, Prague 2, 128 44, Czech Republic.
Isabelle LouradourInstitut Pasteur, Université Paris Cité, INSERM U1201, Unité de Parasitologie moléculaire et Signalisation, F-75015 Paris, France.
Katerina PruzinovaDepartment of Parasitology, Faculty of Science, Charles University, Prague 2, 128 44, Czech Republic.ORCID 0000-0003-1350-4251
Jovana SadlovaDepartment of Parasitology, Faculty of Science, Charles University, Prague 2, 128 44, Czech Republic.ORCID 0000-0002-0432-2707
Petr VolfDepartment of Parasitology, Faculty of Science, Charles University, Prague 2, 128 44, Czech Republic.
Gerald F SpäthInstitut Pasteur, Université Paris Cité, INSERM U1201, Unité de Parasitologie moléculaire et Signalisation, F-75015 Paris, France.ORCID 0000-0002-0256-2029
Charles University · CZInserm · FRInstitut Pasteur · FR

Funding

EC | European Regional Development Fund (ERDF) CZ.02.1.01/0.0/0.0/16_019/0000759EC | H2020 | PRIORITY 'Excellent science' | H2020 Marie Skłodowska-Curie Actions (MSCA) REP-778298-1Institut Pasteur S-FB14002-74A
6 · The paper itself

Abstract

Trypanosomatid pathogens are transmitted by blood-feeding insects, causing devastating human infections. These parasites show important phenotypic shifts that often impact parasite pathogenicity, tissue tropism, or drug susceptibility. The evolutionary mechanisms that allow for the selection of such adaptive phenotypes remain only poorly investigated. Here, we use

Indexed as

Leishmania donovaniPsychodidaeAnimalsDNA RepairHumansMutationOxidative Stressallelic selectionLeishmaniasand fly infection

Identifiers

PMID36848551
PMCPMC10013807
OpenAlexW4322490047

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.