Evidence mapPaperPMID 36858771Full record

ArticleAdvances in pharmacology (San Diego, Calif.)2023

Tungsten toxicity and carcinogenesis.

Alicia M Bolt

Open access · greenAbstract read
In one paragraph

Article in Advances in pharmacology (San Diego, Calif.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
14.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Alicia M BoltCollege of Pharmacy, Department of Pharmaceutical Sciences, The University of New Mexico, Albuquerque, NM, United States. Electronic address: ambolt@salud.unm.edu.
University of New Mexico · US

Funding

UNM Metals Exposure and Toxicity Assessment on tribal Lands in the Southwest (METALS) Superfund Research ProgramP42ES025589 · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · 2025 to 2025
$3.6M
University of New Mexico Center for Metals in Biology and MedicineP20GM130422 · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · 2025 to 2025
$2.3M
Pilot Project CoreP30ES032755 · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · 2025 to 2025
$1.3M
NIEHS NIH HHS P30 ES032755NIEHS NIH HHS P42 ES025589NIEHS NIH HHS R03 ES031724NIGMS NIH HHS P20 GM130422
6 · The paper itself

Abstract

Tungsten is an emerging contaminant in the environment. Research has demonstrated that humans are exposed to high levels of tungsten in certain settings, primarily due to increased use of tungsten in industrial applications. However, our understanding of the potential human health risks of tungsten exposure is still limited. An important point we have learned about the toxicity profile of tungsten is that it is complex because tungsten can often augment the effects of other co-exposures or co-stressors, which could result in greater toxicity or more severe disease. This has shaped the tungsten toxicology field and the types of research questions being investigated. This has particularly been true when evaluating the toxicity profile of tungsten metal alloys in combination with cobalt. In this chapter, the current state of the tungsten toxicology field will be discussed focusing on data investigating tungsten carcinogenicity and other major toxicities including pulmonary, cardiometabolic, bone, and immune endpoints, either alone or in combination with other metals. Environmental and human monitoring data will also be discussed to highlight human populations most at risk of exposure to high concentrations of tungsten, the forms of tungsten present in each setting, and exposure levels in each population.

Indexed as

CarcinogenesisTungstenHumansTungstenBiomonitoringBoneCarcinogenesisMetalToxicityTumorigenesisTungsten

Identifiers

PMID36858771
PMCPMC11003356
OpenAlexW4312891755

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.