Evidence map›Paper›PMID 36858928›Full record

ReviewThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2023

An NIMH Workshop on Non-Affective Psychosis in Midlife and Beyond: Research Agenda on Phenomenology, Clinical Trajectories, Underlying Mechanisms, and Intervention Targets.

Ellen E Lee, David H Adamowicz, Sophia Frangou, Members of the NIMH Workshop on Non-Affective Psychosis in Midlife and Beyond

Abstract readReview
In one paragraph

Review in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ellen E LeeDepartment of Psychiatry (EEL, DA), University of California San Diego, La Jolla, CA; Sam and Rose Stein Institute for Research on Aging (EEL, DA), University of California San Diego, La Jolla, CA; Desert-Pacific Mental Illness Research Education and Clinical Center, Veterans Affairs San Diego Healthcare System (EEL), San Diego, CA. Electronic address: eel013@health.ucsd.edu.
David H AdamowiczDepartment of Psychiatry (EEL, DA), University of California San Diego, La Jolla, CA; Sam and Rose Stein Institute for Research on Aging (EEL, DA), University of California San Diego, La Jolla, CA.
Sophia FrangouDepartment of Psychiatry (SF), University of British Columbia, Vancouver, British Columbia, Canada; Icahn School of Medicine at Mount Sinai (SF), New York, NY.
Members of the NIMH Workshop on Non-Affective Psychosis in Midlife and Beyond

Funding

Psychiatry Research Residency Training TrackR25MH101072 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NEAL R SWERDLOW · 2013 to 2026
$2.8M
Cognitive Consequences of Obstructive Sleep Apnea in Schizophrenia: An Investigation of Inflammatory MechanismsR01MH135147 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ellen Eun-Ok Lee · 2024 to 2026
$2.2M
Inflammatory Mechanisms Linking Sleep Disturbances and Cognitive Deficits in Schizophrenia in Later LifeK23MH119375 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LEE, ELLEN EUN-OK · 2019 to 2023
$1.0M
NIMH NIH HHS K23 MH119375NIMH NIH HHS R01 MH135147NIMH NIH HHS R25 MH101072
6 · The paper itself

Abstract

We present a review of the state of the research in the phenomenology, clinical trajectories, biological mechanisms, aging biomarkers, and treatments for middle-aged and older people with schizophrenia (PwS) discussed at the NIMH sponsored workshop "Non-affective Psychosis in Midlife and Beyond." The growing population of PwS has specific clinical needs that require tailored and mechanistically derived interventions. Differentiating between the effects of aging and disease progression is a key challenge of studying older PwS. This review of the workshop highlights the recent findings in this understudied clinical population and the critical gaps in knowledge and consensus for research priorities. This review showcases the major challenges and opportunities for research to advance clinical care for this growing and understudied population.

Indexed as

Psychotic DisordersSchizophreniaAgedAgingConsensusHumansMiddle AgedNational Institute of Mental Health (U.S.)United StatesagingbiomarkerscognitionSchizophreniatreatment

Identifiers

PMID36858928
PMCPMC10990076

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.