Evidence map›Paper›PMID 36859473›Full record

ReviewMolecules and cells2023

Epigenetic Regulations in Mammalian Cells: Roles and Profiling Techniques.

Uijin Kim, Dong-Sung Lee

Abstract readReview
In one paragraph

Review in Molecules and cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Epigenetics of Skeletal Muscle Atrophy.International journal of molecular sciences · 2024
    Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Uijin KimDepartment of Life Science, University of Seoul, Seoul 02504, Korea.ORCID https://orcid.org/0000-0003-1576-5391
Dong-Sung LeeDepartment of Life Science, University of Seoul, Seoul 02504, Korea.ORCID https://orcid.org/0000-0003-3815-7057

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genome is almost identical in all the cells of the body. However, the functions and morphologies of each cell are different, and the factors that determine them are the genes and proteins expressed in the cells. Over the past decades, studies on epigenetic information, such as DNA methylation, histone modifications, chromatin accessibility, and chromatin conformation have shown that these properties play a fundamental role in gene regulation. Furthermore, various diseases such as cancer have been found to be associated with epigenetic mechanisms. In this study, we summarized the biological properties of epigenetics and single-cell epigenomic profiling techniques, and discussed future challenges in the field of epigenetics.

Indexed as

ChromatinEpigenesis, GeneticAnimalsDNA MethylationEpigenomicsMammalsProtein Processing, Post-TranslationalChromatin3D chromatin structureDNA methylationhistone modificationRNA modificationsingle-cell epigenomics

Identifiers

PMID36859473
PMCPMC9982057

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.