ArticleFrontiers in neurology2023
Repetitive transcranial magnetic stimulation over the posterior parietal cortex improves functional recovery in nonresponsive patients: A crossover, randomized, double-blind, sham-controlled study.
Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05187000 (Effect of Individualized Repetitive Transcranial Magnetic Stimulation), which is not on this map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Individualized Repetitive Transcranial Magnetic Stimulation (rTMS) in Patients With Disorder of Consciousness
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Noninvasive neuromodulation for disorders of consciousness: an updated systematic review and meta-analysis.Critical care (London, England) · 2025Pooled it
- Effects of non-invasive brain stimulation on arousal and alertness among traumatic brain injury patients with disorders of consciousness or persistent vegetative State: a systematic review.Acta neurologica Belgica · 2025Pooled it
- Efficacy of non-pharmacological treatments for prolonged disorders of consciousness: a network meta-analysis of randomized controlled trials.Frontiers in neurologyPooled it
- Can repetitive transcranial magnetic stimulation promote recovery of consciousness in patients with disorders of consciousness? A randomized controlled trial.NeuroImage. Clinical · 2025Trial
- Perturbational complexity index in assessing responsiveness to rTMS treatment in patients with disorders of consciousness: a cross-over randomized controlled trial study.Journal of neuroengineering and rehabilitation · 2024Trial
- Effect and mechanism of repetitive transcranial magnetic stimulation of angular gyrus on patients with consciousness disorder.Frontiers in neurologyTrial
- Neural Circuit Mechanisms of Disorders of Consciousness and Potential Therapeutic Targets of Brain Stimulation.CNS neuroscience & therapeutics · 2026Review
- EEG hemispheric asymmetry and behavioral responsiveness following rTMS in unresponsive wakefulness syndrome: an exploratory study.Journal of neuroengineering and rehabilitation · 2026Article
- State-dependent repetitive transcranial magnetic stimulation in disorders of consciousness.Frontiers in human neuroscience · 2026Review
- Non-invasive neuroregulation techniques applied to patients with consciousness disorders: a narrative review.Frontiers in human neuroscience · 2026Review
- Parietal rTMS Induced Changes in Cortical Excitability in Patients With Minimally Conscious State Using TMS-EEG.CNS neuroscience & therapeutics · 2025Article
- Efficacy of repetitive transcranial magnetic stimulation for disorders of consciousness: a retrospective cohort study.Frontiers in neurology · 2025Article
- Bilateral dorsolateral prefrontal cortex high-frequency transcranial magnetic stimulation for consciousness recovery after traumatic brain injury: a case series.Frontiers in psychiatry · 2025Article
- Brain health: A concern for anaesthesiologists and intensivists.European journal of anaesthesiology and intensive care · 2024Review
- Brain state identification and neuromodulation to promote recovery of consciousness.Brain communications · 2024Review
- Differences in the effect of repetitive transcranial magnetic stimulation and median nerve electrical stimulation in patients with prolonged disorders of consciousness after intracerebral hemorrhage: a randomized controlled trial protocol.Frontiers in neurology · 2024Article
- Behavioral Effects of Repetitive Transcranial Magnetic Stimulation in Disorders of Consciousness: A Systematic Review and Meta-Analysis.Brain sciences · 2023Review
- A protocol for a multicenter randomized and personalized controlled trial using rTMS in patients with disorders of consciousness.Frontiers in neurology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Recent studies have shown that patients with disorders of consciousness (DoC) can benefit from repetitive transcranial magnetic stimulation (rTMS) therapy. The posterior parietal cortex (PPC) is becoming increasingly important in neuroscience research and clinical treatment for DoC as it plays a crucial role in the formation of human consciousness. However, the effect of rTMS on the PPC in improving consciousness recovery remains to be studied. Method: We conducted a crossover, randomized, double-blind, sham-controlled clinical study to assess the efficacy and safety of 10 Hz rTMS over the left PPC in unresponsive patients. Twenty patients with unresponsive wakefulness syndrome were recruited. The participants were randomly divided into two groups: one group received active rTMS treatment for 10 consecutive days ( Result: rTMS-active treatment resulted in a significant improvement in the CRS-R total score ( Conclusions: This study suggests that 10 Hz rTMS over the left PPC can significantly improve functional recovery in unresponsive patients with DoC, with no reported side effects. Clinical trial registration: www.ClinicalTrials.gov, identifier: NCT05187000.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.