Evidence map›Paper›PMID 36876127›Full record

ArticleiScience2023

Successful naltrexone-bupropion treatment after several treatment failures in a patient with severe monogenic obesity.

Mila S Welling, Mostafa Mohseni, Eline S van der Valk, Johanna M van Hagen, Jan Steven Burgerhart, Mieke M van Haelst, Elisabeth F C van Rossum

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Mila S WellingDepartment of Internal Medicine, Division of Endocrinology, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, South-Holland, the Netherlands.
Mostafa MohseniDepartment of Internal Medicine, Division of Endocrinology, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, South-Holland, the Netherlands.
Eline S van der ValkDepartment of Internal Medicine, Division of Endocrinology, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, South-Holland, the Netherlands.
Johanna M van HagenDepartment of Human Genetics, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, North-Holland, the Netherlands.
Jan Steven BurgerhartDepartment of Internal Medicine, University Medical Center Utrecht, 3584 CX Utrecht, Utrecht, the Netherlands.
Mieke M van HaelstDepartment of Human Genetics, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, North-Holland, the Netherlands.
Elisabeth F C van RossumDepartment of Internal Medicine, Division of Endocrinology, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, South-Holland, the Netherlands.
Erasmus MC · NLAmsterdam University Medical Centers · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe the therapeutic journey of a 33-year-old patient with early-onset obesity (BMI 56.7 kg/m

Indexed as

Biological sciencesHuman metabolismHuman PhysiologyPhysiology

Identifiers

PMID36876127
PMCPMC9982263
OpenAlexW4320717154

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.