Evidence map›Paper›PMID 36879464›Full record

ReviewEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2023

STereotactic Arrhythmia Radioablation (STAR): the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe.

Melanie Grehn, Stefano Mandija, Marcin Miszczyk, David Krug, Bartłomiej Tomasik, Kristine E Stickney, Pino Alcantara, Filippo Alongi, Matteo Anselmino, Ricardo Salgado Aranda and 43 more

Open access · hybridAbstract readReview
In one paragraph

Review in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
14.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Stereotactic cardiac radiotherapy for refractory ventricular tachycardia in structural heart disease patients: a systematic review.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Pooled it
  3. Trial
  4. Linear accelerator-based stereotactic arrhythmia radioablation for paroxysmal atrial fibrillation in elderly: a prospective phase II trial.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Trial
  5. Development of a prospective clinical workflow for proton beam therapy of ventricular tachycardia.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Article
  6. Review
  7. Article
  8. Article
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  10. Article
  11. Article
  12. Article
  13. Article
  14. Stereotactic radioablation for ventricular tachycardia in patients untreatable by catheter ablation: evidence of efficacy, safety, and impact on coronary arteries.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  15. Left Ventricular Motion Analysis Framework for the MATRIX-VT Study.International journal of computer assisted radiology and surgery · 2026
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Rethinking imaging protocols, training models, and target delineation in cardiac radioablation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

53 authors at 20 institutions in 8 countries.

Melanie GrehnDepartment of Radiation Oncology, University Medical Center Schleswig-Holstein, Arnold-Heller-Strasse 3, Kiel 24105, Germany.ORCID 0000-0002-6170-5122
Stefano MandijaDepartment of Radiotherapy, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands.ORCID 0000-0002-4612-5509
Marcin MiszczykIIIrd Radiotherapy and Chemotherapy Department, Maria Skłodowska-Curie National Research Institute of Oncology, Ul. Wybrzeze Armii Krajowej, Gliwice 44102, Poland.ORCID 0000-0002-4375-0827
David KrugDepartment of Radiation Oncology, University Medical Center Schleswig-Holstein, Arnold-Heller-Strasse 3, Kiel 24105, Germany.ORCID 0000-0001-8811-5416
Bartłomiej TomasikDepartment of Radiotherapy, Maria Skłodowska-Curie National Research Institute of Oncology, Ul. Wybrzeze Armii Krajowej, Gliwice 44102, Poland.ORCID 0000-0001-5648-345X
Kristine E StickneyResearch Support Office, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands.
Pino AlcantaraDepartment of Radiation Oncology, Hospital Clínico San Carlos, Faculty of Medicine, University Complutense of Madrid, Profesor Martin Lagos, Madrid 28040, Spain.ORCID 0000-0001-5744-9480
Filippo AlongiDepartment of Advanced Radiation Oncology, IRCCS Sacro Cuore Don Calabria Hospital, University of Brescia, Via San Zeno in Monte 23, Verona 37129, Italy.
Matteo AnselminoDivision of Cardiology, Cardiovascular and Thoracic Department, 'Città della Salute e della Scienza' Hospital, Via Giuseppe Verdi 8, Torino 10124, Italy.ORCID 0000-0002-6311-4270
Ricardo Salgado ArandaElectrophysiology Unit, Department of Cardiology, Hospital Clínico San Carlos Madrid, Professor Martin Lagos, Madrid 28040, Spain.ORCID 0000-0002-2627-8436
Brian V BalgobindDepartment of Radiation Oncology, Amsterdam UMC, University of Amsterdam, Meibergdreef 15, Amsterdam 1105AZ, The Netherlands.
Judit Boda-HeggemannDepartment of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, Mannheim 68167, Germany.
Leif-Hendrik BoldtDepartment of Rhythmology, Charité-University Medicine Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Nicola BottoniCardiology Arrhythmology Center, AUSL-IRCCS di Reggio Emilia, Via Amendola 2, Reggio Emilia 42100, Italy.
Jakub CvekDepartment of Oncology, University Hospital and Faculty of Medicine, Listopadu 1790, Ostrava Poruba 70852, Czech Republic.ORCID 0000-0003-1579-1792
Olgun ElicinDepartment of Radiation Oncology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 18, Bern 3010, Switzerland.ORCID 0000-0002-6996-0646
Gaetano Maria De FerrariDivision of Cardiology, Cardiovascular and Thoracic Department, 'Città della Salute e della Scienza' Hospital, Via Giuseppe Verdi 8, Torino 10124, Italy.ORCID 0000-0003-4940-0876
Rutger J HassinkDepartment of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht University, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands.ORCID 0000-0003-0237-7867
Colien HazelaarDepartment of Radiation Oncology (Maastro), GROW School for Oncology and Reproduction, Maastricht University Medical Centre+, P. Debyelaan 25, Maastricht 6229 HX, The Netherlands.
Gerhard HindricksDepartment of Electrophysiology, Heart Center Leipzig, University of Leipzig, Struempellstrasse 39, Leipzig 04289, Germany.ORCID 0000-0002-0132-0773
Coen HurkmansDepartment of Radiation Oncology, Catharina Hospital, Michelangelolaan 2, Eindhoven 5623 EJ, The Netherlands.ORCID 0000-0003-2268-0492
Cinzia IottiRadiation Oncology Unit, Clinical Cancer Centre, AUSL-IRCCS di Reggio Emilia, Via Amendola 2, Reggio Emilia 42100, Italy.ORCID 0000-0001-9686-7298
Tomasz JadczykDivision of Cardiology and Structural Heart Diseases, Medical University of Silesia, Ul. Poniatowskiego 15, Katowice 40055, Poland.ORCID 0000-0002-7955-9100
Otakar JiravskyCardiocenter, Hospital Agel Trinec Podlesi and Masaryk University, Konska 453, Trinec 73961, Czech Republic.ORCID 0000-0001-9334-5734
Raphaël JumeauDepartment of Radio-Oncology, Lausanne University Hospital, Rue du Bugnon 21, Lausanne 1011, Switzerland.ORCID 0000-0002-0098-8835
Steen Buus KristiansenDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, Aarhus 8200, Denmark.
Mario LevisDepartment of Oncology, University of Torino, Via Giuseppe Verdi 8, Torino 10124, Italy.ORCID 0000-0002-7668-3296
Manuel Algara LópezDepartment of Radiation Oncology, Hospital del Mar, Universitat Pompeu Fabra, Institut Hospital del Mar d'Investigacions Mèdiques, Paseo Maritim 25-29, Barcelona 08003, Spain.ORCID 0000-0002-0500-9202
Julio Martí-AlmorDepartment of Cardiology, Hospital del Mar, Universitat Pompeu Fabra, Institut Hospital del Mar d'Investigacions Mèdiques, Paseo Maritim 25-29, Barcelona 08003, Spain.ORCID 0000-0001-9927-1190
Felix MehrhofDepartment for Radiation Oncology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.ORCID 0000-0003-0553-4290
Ditte Sloth MøllerDepartment of Oncology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, Aarhus 8200, Denmark.ORCID 0000-0001-9910-515X
Giulio MolonDepartment of Cardiology, IRCCS Sacro Cuore Don Calabria Hospital, Via San Zeno in Monte 23, Verona 37129, Italy.ORCID 0000-0001-8287-0461
Alexandre OussDepartment of Cardiology, Catharina Hospital, Michelangelolaan 2, Eindhoven 5623 EJ, The Netherlands.ORCID 0000-0001-7405-822X
Petr PeichlDepartment of Cardiology, Institute for Clinical and Experimental Medicine, Videnska 9, Prague 14000, Czech Republic.ORCID 0000-0002-5625-0071
Jiri PlasekDepartment of Cardiovascular Medicine, University Hospital Ostrava, Listopadu 1790. Ostrava Poruba 70852, Czech Republic.
Pieter G PostemaDepartment of Cardiology, Amsterdam UMC, University of Amsterdam, Meibergdreef 15, Amsterdam 1105AZ, The Netherlands.ORCID 0000-0003-2863-9159
Aurelio QuesadaArrhythmia Unit, Department of Cardiology, Consorcio Hospital General Universitario de Valencia, Av Tres Cruces 2, Valencia 46014, Spain.ORCID 0000-0003-4709-1993
Tobias ReichlinDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 18, Bern 3010, Switzerland.ORCID 0000-0002-7197-8415
Roberto RordorfCardiac Intensive Care Unit, Arrhythmia and Electrophysiology and Experimental Cardiology, Fondazione IRCCS Policlinico San Matteo, Camillo Golgi Avenue 5, Pavia 27100, Italy.ORCID 0000-0003-4111-1690
Boris RudicDepartment of Medicine I, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, Mannheim 68167, Germany.ORCID 0000-0002-2275-7149
Ardan M SagunerArrhythmia Unit, Department of Cardiology, University Hospital Zurich, Ramistrasse 71, Zurich 8006, Switzerland.
Rachel M A Ter BekkeDepartment of Cardiology, Maastricht University Medical Center, P. Debyelaan 25, Maastricht 6229 HX, The Netherlands.ORCID 0000-0003-4278-0132
José López TorrecillaDepartment of Radiation Oncology, Hospital General Valencia, Av Tres Cruces 2, Valencia 46014, Spain.ORCID 0000-0002-6012-1694
Esther G C TroostDepartment of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, Dresden 01307, Germany.
Viviana VitoloNational Center of Oncological Hadrontherapy (Fondazione CNAO), Strada Campeggi 53, Pavia PV27100, Italy.ORCID 0000-0001-7833-827X
Nicolaus AndratschkeDepartment of Radiation Oncology, University Hospital of Zurich, Ramistrasse 71, Zurich 8006, Switzerland.ORCID 0000-0003-3647-5916
Katja ZeppenfeldUnit of Clinical Electrophysiology, Leiden University Medical Center, Albinusdreef 2, Leiden 2333 ZA, The Netherlands.ORCID 0000-0001-6645-082X
Slawomir BlamekDepartment of Radiotherapy, Maria Skłodowska-Curie National Research Institute of Oncology, Ul. Wybrzeze Armii Krajowej, Gliwice 44102, Poland.ORCID 0000-0002-0585-9100
Martin FastDepartment of Radiotherapy, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands.ORCID 0000-0001-9107-4627
Ludovica de PanfilisBioethics Unit, Azienda Unità Sanitaria Locale-IRCCS, Via Amendola 2, Reggio Emilia 42100, Italy.ORCID 0000-0002-5509-7626
Oliver BlanckDepartment of Radiation Oncology, University Medical Center Schleswig-Holstein, Arnold-Heller-Strasse 3, Kiel 24105, Germany.
Etienne PruvotHeart and Vessel Department, Service of Cardiology, Lausanne University Hospital and University of Lausanne, Rue du Bugnon 21, Lausanne 1011, Switzerland.ORCID 0000-0003-1386-9285
Joost J C VerhoeffDepartment of Radiotherapy, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands.ORCID 0000-0001-9673-0793
Heidelberg University · DEAzienda Sanitaria Unità Locale di Reggio Emilia · ITThe Maria Sklodowska-Curie National Research Institute of Oncology · PLUniversity Hospital Schleswig-Holstein · DEAarhus University Hospital · DKAmsterdam University Medical Centers · NLAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITCharité - Universitätsmedizin Berlin · DEHospital Clínico San Carlos · ESHospital General Universitario De Valencia · ESOspedale Sacro Cuore Don Calabria · ITRadboud University Nijmegen · NLUniversitat Pompeu Fabra · ESUniversity Hospital of Zurich · CHUniversity Hospital Ostrava · CZUniversity of Bern · CHUniversity of Lausanne · CHHelmholtz-Zentrum Dresden-Rossendorf · DEInstitute of Clinical and Experimental Medicine · CZLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The EU Horizon 2020 Framework-funded Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary (STOPSTORM) consortium has been established as a large research network for investigating STereotactic Arrhythmia Radioablation (STAR) for ventricular tachycardia (VT). The aim is to provide a pooled treatment database to evaluate patterns of practice and outcomes of STAR and finally to harmonize STAR within Europe. The consortium comprises 31 clinical and research institutions. The project is divided into nine work packages (WPs): (i) observational cohort; (ii) standardization and harmonization of target delineation; (iii) harmonized prospective cohort; (iv) quality assurance (QA); (v) analysis and evaluation; (vi, ix) ethics and regulations; and (vii, viii) project coordination and dissemination. To provide a review of current clinical STAR practice in Europe, a comprehensive questionnaire was performed at project start. The STOPSTORM Institutions' experience in VT catheter ablation (83% ≥ 20 ann.) and stereotactic body radiotherapy (59% > 200 ann.) was adequate, and 84 STAR treatments were performed until project launch, while 8/22 centres already recruited VT patients in national clinical trials. The majority currently base their target definition on mapping during VT (96%) and/or pace mapping (75%), reduced voltage areas (63%), or late ventricular potentials (75%) during sinus rhythm. The majority currently apply a single-fraction dose of 25 Gy while planning techniques and dose prescription methods vary greatly. The current clinical STAR practice in the STOPSTORM consortium highlights potential areas of optimization and harmonization for substrate mapping, target delineation, motion management, dosimetry, and QA, which will be addressed in the various WPs.

Indexed as

Catheter AblationTachycardia, VentricularArrhythmias, CardiacHeart VentriclesHumansProspective StudiesTreatment OutcomeCardiac arrhythmiasConsortiumEU Horizon 2020Stereotactic arrhythmia radioablationStereotactic body radiotherapyVentricular tachycardia

Identifiers

PMID36879464
PMCPMC10105846
OpenAlexW4323347896

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.