Evidence map›Paper›PMID 36883454›Full record

SynthesisHypertension (Dallas, Tex. : 1979)2023

Effectiveness and Cost-Effectiveness of Team-Based Care for Hypertension: A Meta-Analysis and Simulation Study.

Kelsey B Bryant, Aditi S Rao, Laura P Cohen, Nadine Dandan, Ian M Kronish, Nikita Barai, Valy Fontil, Yiyi Zhang, Andrew E Moran, Brandon K Bellows

Registry-linked trialAbstract readMeta-Analysis
In one paragraph

Synthesis in Hypertension (Dallas, Tex. : 1979), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07397260 (Effects of Manually Recorded or Automatically Transmitted Home Blood Pressures With or Without Automated Patient Feedback on Hypertension Care), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07397260 naenrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Effects of Manually Recorded or Automatically Transmitted Home Blood Pressures With or Without Automated Patient Feedback on Hypertension Care

TypeinterventionalSponsorNorthwestern UniversityRan2026 to 2028Enrolled1,304ConditionsHypertension (HTN)ArmsSelf report of home measured blood pressure via patient EHR portal, Automated feedback about home blood pressure results, Automated Transmission of Remotely Measured Blood Pressure
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Impact of patient care teams on blood pressure control in patients with hypertension: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Pooled it
  2. Review
  3. Article
  4. Article
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  10. The Japanese Society of Hypertension Guidelines for the management of elevated blood pressure and hypertension 2025 (JSH2025).Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Expanding team-based care for hypertension and cardiovascular risk management with HEARTS in the Americas.Revista panamericana de salud publica = Pan American journal of public health · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Kelsey B Bryant *Icahn School of Medicine, Mount Sinai, New York, NY (K.B.B., N.B.).ORCID 0000-0001-7180-8064
Aditi S Rao *Vagelos College of Physicians and Surgeons, Columbia University, New York, NY (A.S.R., L.P.C., I.M.K., Y.Z., A.E.M., B.K.B.).
Laura P CohenVagelos College of Physicians and Surgeons, Columbia University, New York, NY (A.S.R., L.P.C., I.M.K., Y.Z., A.E.M., B.K.B.).ORCID 0000-0003-1384-5849
Nadine DandanNew York-Presbyterian Hospital, Columbia University Medical Center, NY (N.D.).
Ian M KronishVagelos College of Physicians and Surgeons, Columbia University, New York, NY (A.S.R., L.P.C., I.M.K., Y.Z., A.E.M., B.K.B.).ORCID 0000-0003-0945-2380
Nikita BaraiIcahn School of Medicine, Mount Sinai, New York, NY (K.B.B., N.B.).
Valy FontilGrossman School of Medicine, New York University, NY (V.F.).ORCID 0000-0003-0795-3237
Yiyi ZhangVagelos College of Physicians and Surgeons, Columbia University, New York, NY (A.S.R., L.P.C., I.M.K., Y.Z., A.E.M., B.K.B.).ORCID 0000-0002-8663-5001
Andrew E MoranVagelos College of Physicians and Surgeons, Columbia University, New York, NY (A.S.R., L.P.C., I.M.K., Y.Z., A.E.M., B.K.B.).ORCID 0000-0003-3554-0085
Brandon K BellowsVagelos College of Physicians and Surgeons, Columbia University, New York, NY (A.S.R., L.P.C., I.M.K., Y.Z., A.E.M., B.K.B.).ORCID 0000-0003-1395-6047

Funding

Implementing Remote Patient Monitoring to Improve Hypertension Control in a Primary Care NetworkR01HL152699 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KRONISH, IAN MATTHEW · 2021 to 2025
$3.5M
Improving Blood Pressure Screening and Treatment Strategies in Young AdultsR01HL158790 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI AN, JAEJIN, ZHANG, YIYI · 2021 to 2025
$3.5M
Model Based Approach to Improving Hypertension Control in PopulationsR01HL130500 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MORAN, ANDREW EDWARD · 2016 to 2019
$2.4M
Bring it Down San Francisco: Harnessing cloud-based technology to improve hypertension management in a low-income underserved populationK23HL136899 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FONTIL, VALY · 2018 to 2022
$887k
Comparing the value of intensive systolic blood pressure treatment implementation strategiesK01HL140170 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BELLOWS, BRANDON K · 2018 to 2022
$709k
NHLBI NIH HHS K01 HL140170NHLBI NIH HHS K23 HL136899NHLBI NIH HHS R01 HL130500NHLBI NIH HHS R01 HL152699NHLBI NIH HHS R01 HL158790
6 · The paper itself

Abstract

backgroundTeam-based care (TBC), a team of ≥2 healthcare professionals working collaboratively toward a shared clinical goal, is a recommended strategy to manage blood pressure (BP). However, the most effective and cost-effective TBC strategy is unknown.

methodsA meta-analysis of clinical trials in US adults (aged ≥20 years) with uncontrolled hypertension (≥140/90 mm Hg) was performed to estimate the systolic BP reduction for TBC strategies versus usual care at 12 months. TBC strategies were stratified by the inclusion of a nonphysician team member who could titrate antihypertensive medications. The validated BP Control Model-Cardiovascular Disease Policy Model was used to project the expected BP reductions out to 10 years and simulate cardiovascular disease events, direct healthcare costs, quality-adjusted life years, and cost-effectiveness of TBC with physician and nonphysician titration.

resultsAmong 19 studies comprising 5993 participants, the 12-month systolic BP change versus usual care was -5.0 (95% CI, -7.9 to -2.2) mm Hg for TBC with physician titration and -10.5 (-16.2 to -4.8) mm Hg for TBC with nonphysician titration. Relative to usual care at 10 years, TBC with nonphysician titration was estimated to cost $95 (95% uncertainty interval, -$563 to $664) more per patient and gain 0.022 (0.003-0.042) quality-adjusted life years, costing $4400/quality-adjusted life year gained. TBC with physician titration was estimated to cost more and gain fewer quality-adjusted life years than TBC with nonphysician titration.

conclusionsTBC with nonphysician titration yields superior hypertension outcomes compared with other strategies and is a cost-effective way to reduce hypertension-related morbidity and mortality in the United States.

Indexed as

Cardiovascular DiseasesHypertensionHypotensionAdultAntihypertensive AgentsBlood PressureCost-Benefit AnalysisHumansAntihypertensive Agentsblood pressurecardiovascular diseaseshypertensionmeta-analysisUnited States

Identifiers

PMID36883454
PMCPMC10987007

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.