Evidence map›Paper›PMID 36888929›Full record

SynthesisJCO global oncology2023

Clinicopathologic Features of Breast Cancer in Egypt-Contemporary Profile and Future Needs: A Systematic Review and Meta-Analysis.

Hamdy A Azim, Hagar Elghazawy, Ramy M Ghazy, Ahmed H Abdelaziz, Marwa Abdelsalam, Amira Elzorkany, Loay Kassem

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in JCO global oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07130162 (Detection of Phosphatidylinositol Glycan Anchor Biosynthesis Class U Protein as Serum Biomarker for Breast Cancer), which is not on this map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07130162 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Detection of Phosphatidylinositol Glycan Anchor Biosynthesis Class U Protein as Serum Biomarker for Breast Cancer

TypeobservationalSponsorAssiut UniversityRan2025 to 2026Enrolled96ConditionsBreast CancerArmsMeasurement of serum PIGU protein concentrations of patients and controls by Enzyme-Linked Immunosorbent Assay (ELISA)
3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hamdy A AzimClinical Oncology Department, Kasr Alainy School of Medicine, Cairo University, Giza, Egypt.
Hagar ElghazawyCairo Oncology Center, Cairo, Egypt.ORCID 0000-0001-6839-4147
Ramy M GhazyTropical Health Department, High Institute of Public Health, Alexandria University, Alexandria, Egypt.ORCID 0000-0001-7611-706X
Ahmed H AbdelazizClinical Oncology Department, Ain Shams University, Cairo, Egypt.ORCID 0000-0002-3162-1825
Marwa AbdelsalamCairo Oncology Center, Cairo, Egypt.
Amira ElzorkanyTraining and Biostatistics Administration, Ministry of Health and Population, Alexandria, Egypt.ORCID 0000-0001-8572-1285
Loay KassemClinical Oncology Department, Kasr Alainy School of Medicine, Cairo University, Giza, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBreast cancer (BC) is the most common cancer among Egyptian females. No current national cancer database is available in Egypt to provide reliable data on the specific clinicopathologic features of BC in this population. Herein, we investigated the clinical profile of BC among Egyptian women.

methodsA systematic review of studies on BC published from inception until December 2021 was performed. We explored pooled estimated proportions of different stages of BC at presentation in Egypt and other clinicopathologic features including age, menopausal status, tumor (T) and lymph node (N) stages, and biological subtypes. Data analysis was performed using meta package (R).

resultsTwenty-six studies were eligible for our systematic review and meta-analysis, including 31,172 BC cases. In 12 studies, including 15,067 patients with BC, the estimated mean age was 50.46 years (95% CI, 48.7 to 52.1; I

conclusionDominance of advanced stage and young age at diagnosis represented the two main features of BC among Egyptian women. Our data may serve to guide the policymakers in Egypt as well as other countries with lower resources to prioritize the diagnostic and therapeutic needs in this context.

Indexed as

Breast NeoplasmsEgyptFemaleHumansMiddle Aged

Identifiers

PMID36888929
PMCPMC10497263

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.