ArticleNature microbiology2023
Lignin deconstruction by anaerobic fungi.
Article in Nature microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 108 citations in OpenAlex.
- Resolving aromatic spectral congestion in whole-cell solid-state NMR: Signatures of condensed tannins and lignin in plant tissues.Cell surface (Amsterdam, Netherlands) · 2026Article
- Dye-Decolorizing Peroxidase for Lignin Depolymerization: a Comprehensive Review on Enzyme Structural Characteristics, Reaction-Influencing Factors and Efficiency-Enhancing Strategies.Applied biochemistry and biotechnology · 2026Review
- Co-amendment of rumen microorganism and bamboo biochar to optimize VFAs synthesis in cornstalk anaerobic fermentation: performance evaluation and mechanism understanding.Bioprocess and biosystems engineering · 2026Article
- Diverse thermophilic anaerobes from Indian hot springs show potential for bioenergy production from lignocellulosic biomass.World journal of microbiology & biotechnology · 2026Article
- Plant Biomass Depolymerization by Oxidoreductases: Structural Characteristics, Synergy Mechanism, and Evolutionary Adaptation.Journal of agricultural and food chemistry · 2026Review
- Sandwich Mycelium-Based Composite Panels Fabricated with a Lightweight Core from Forest Waste UsingJournal of fungi (Basel, Switzerland) · 2026Article
- Nonenergy Biomass Carbon Removal and Storage (BiCRS): Assessing Durability of Nongaseous Carbon Products Across Terrestrial Storage Fates.Chemical reviews · 2026Review
- The oleaginous yeast Cutaneotrichosporon oleaginosum modifies corn stover alkali lignin.Scientific reports · 2026Article
- Deep subsurface organic-rich shale supports abundant, diverse, and novel fungi.The ISME journal · 2026Article
- Lignin enrichment selects specialized fungal communities from contrasting soils.Sustainable microbiology · 2026Article
- Silent bacteria: Intrinsic bioremediation potential in the sediments of Lake Faro (Messina, Italy).AIMS microbiology · 2026Article
- Advances in Lignocellulose-Degrading Enzyme Discovery from Anaerobic Rumen Fungi.Microorganisms · 2025Review
- Uncovering enzymatic tools promoting lignocellulose breakdown in the anaerobic bacterium Ruminiclostridium cellulolyticum.Communications biology · 2025Article
- Review
- A genomic perspective on fungal diversity and evolution.Nature reviews. Microbiology · 2025Review
- Article
- The anaerobic fungus Neocallimastix californiae shifts metabolism and produces melanin in response to lignin-derived aromatic compounds.Biotechnology for biofuels and bioproducts · 2025Article
- Untargeted GC-MS Metabolic Profiling of Anaerobic Gut Fungi Reveals Putative Terpenoids and Strain-Specific Metabolites.Metabolites · 2025Article
- The Effects of the Substrate Length and Cultivation Time on the Physical and Mechanical Properties of Mycelium-Based Cushioning Materials fromBiomimetics (Basel, Switzerland) · 2025Article
- An In Vitro Nutritional Evaluation of Mixed Silages of Drought-Impaired Grass and Sugar Beet Pulp With or Without Silage Inoculants.Journal of animal physiology and animal nutrition · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 7 institutions in 3 countries.
Funding
Abstract
Lignocellulose forms plant cell walls, and its three constituent polymers, cellulose, hemicellulose and lignin, represent the largest renewable organic carbon pool in the terrestrial biosphere. Insights into biological lignocellulose deconstruction inform understandings of global carbon sequestration dynamics and provide inspiration for biotechnologies seeking to address the current climate crisis by producing renewable chemicals from plant biomass. Organisms in diverse environments disassemble lignocellulose, and carbohydrate degradation processes are well defined, but biological lignin deconstruction is described only in aerobic systems. It is currently unclear whether anaerobic lignin deconstruction is impossible because of biochemical constraints or, alternatively, has not yet been measured. We applied whole cell-wall nuclear magnetic resonance, gel-permeation chromatography and transcriptome sequencing to interrogate the apparent paradox that anaerobic fungi (Neocallimastigomycetes), well-documented lignocellulose degradation specialists, are unable to modify lignin. We find that Neocallimastigomycetes anaerobically break chemical bonds in grass and hardwood lignins, and we further associate upregulated gene products with the observed lignocellulose deconstruction. These findings alter perceptions of lignin deconstruction by anaerobes and provide opportunities to advance decarbonization biotechnologies that depend on depolymerizing lignocellulose.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.