Evidence map›Paper›PMID 36894879›Full record

Trial reportBMC cardiovascular disorders2023

Left atrial dysfunction can independently predict exercise capacity in patients with chronic heart failure who use beta-blockers.

Pengtao Sun, Huan Cen, Sinan Chen, Xiankun Chen, Wei Jiang, Huiying Zhu, Yuexia Liu, Hongmei Liu, Weihui Lu

Registry-linked trialOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in BMC cardiovascular disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03180320 (Effect of an Exercise-based Cardiac Rehabilitation Program 'Baduanjin-eight-silken-movement With Self-efficacy Building' for Patients With Chronic Heart Failure in Guangzhou, China), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03180320 narecruitingnot on this map

Effect of an Exercise-based Cardiac Rehabilitation Program 'Baduanjin-eight-silken-movement With Self-efficacy Building' for Patients With Chronic Heart Failure in Guangzhou, China (BESMILE-HF Study)

TypeinterventionalSponsorGuangdong Provincial Hospital of Traditional Chinese MedicineRan2018 to 2026Enrolled150ConditionsHeart Failure NYHA Class II, Heart Failure NYHA Class III, Heart FailureArmsBESMILE-HF program, Usual medications
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Pengtao Sun *The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510000, China.
Huan Cen *The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510000, China.
Sinan ChenThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510000, China.
Xiankun ChenState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510000, China.
Wei JiangThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510000, China.
Huiying ZhuThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510000, China.
Yuexia LiuThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510000, China.
Hongmei LiuThe Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510000, China. hongmeiliu3@163.com.
Weihui LuThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510000, China. weihui.lu@163.com.
Guangzhou University of Chinese Medicine · CNGuangdong Provincial Hospital of Traditional Chinese Medicine · CNSouthern Medical University · CN

Funding

the Clinical Research Fund of the Traditional Chinese Medicine Science and Technology (Project 1010) from GPHCM YN10101910the General Research Fund of Traditional Chinese Medicine Science and Technology from the Guangdong Provincial Hospital of Chinese Medicine YN2018ML02the Research Fund from the Guangdong Traditional Chinese Medicine Health Service and Industry Development Center 2021YJZX014
6 · The paper itself

Abstract

backgroundBeta-blockers are first-line clinical drugs for the treatment of chronic heart failure (CHF). In the guidelines for cardiac rehabilitation, patients with heart failure who do or do not receive beta-blocker therapy have different reference thresholds for maximal oxygen uptake (VO

methodsThis cross-sectional study enrolled 73 patients with CHF who received beta-blockers. All patients underwent a thorough resting echocardiogram and a cardiopulmonary exercise test to obtain VO

resultsLA reservoir strain, LA maximum volume index (LAVI

conclusionAmong CHF patients receiving beta-blocker therapy, resting LA strain is linearly correlated with exercise capacity. LA reservoir strain is a robust independent predictor of reduced exercise capacity among all resting echocardiography parameters. CLINICAL

trial registrationThis study is a part of the Baduanjin-Eight-Silken-Movement with Self-efficacy Building for Patients with Chronic Heart Failure (BESMILE-HF) trial NCT03180320 (ClinicalTrials.gov, registration date: 08/06/2017).

Indexed as

Atrial FibrillationHeart FailureCross-Sectional StudiesExercise TestExercise ToleranceHeart AtriaHumansStroke VolumeVentricular Function, LeftBeta-blockersChronic heart failureExercise capacityLeft atrial strainMaximal oxygen uptake

Identifiers

PMID36894879
PMCPMC9996944
OpenAlexW4323662742

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.