Evidence map›Paper›PMID 36896830›Full record

ArticleESC heart failure2023

Prognostic role of pulmonary impedance estimation to predict right ventricular dysfunction in pulmonary hypertension.

Sara Louise Hungerford, Katherine Kearney, Ning Song, Nicole Bart, Eugene Kotlyar, Edmund Lau, Andrew Jabbour, Christopher Simon Hayward, David William Marshall Muller, Audrey Adji

Open access · goldAbstract read
In one paragraph

Article in ESC heart failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Sara Louise HungerfordDepartment of Cardiology, St Vincent's Hospital, Darlinghurst, Australia.ORCID 0000-0003-0040-7719
Katherine KearneyDepartment of Cardiology, St Vincent's Hospital, Darlinghurst, Australia.
Ning SongDepartment of Cardiology, St Vincent's Hospital, Darlinghurst, Australia.
Nicole BartDepartment of Cardiology, St Vincent's Hospital, Darlinghurst, Australia.
Eugene KotlyarDepartment of Cardiology, St Vincent's Hospital, Darlinghurst, Australia.
Edmund LauDepartment of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney, Australia.
Andrew JabbourDepartment of Cardiology, St Vincent's Hospital, Darlinghurst, Australia.
Christopher Simon HaywardDepartment of Cardiology, St Vincent's Hospital, Darlinghurst, Australia.
David William Marshall MullerDepartment of Cardiology, St Vincent's Hospital, Darlinghurst, Australia.
Audrey AdjiDepartment of Cardiology, St Vincent's Hospital, Darlinghurst, Australia.
Victor Chang Cardiac Research Institute · AURoyal Prince Alfred Hospital · AUSt Vincent's Hospital Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe effect of pulmonary hypertension (PH) on right ventricular (RV) afterload is commonly defined by elevation of pulmonary artery (PA) pressure or pulmonary vascular resistance (PVR). In humans however, one-third to half of the hydraulic power in the PA is contained in pulsatile components of flow. Pulmonary impedance (Zc) expresses opposition of the PA to pulsatile blood flow. We evaluate pulmonary Zc relationships according to PH classification using a cardiac magnetic resonance (CMR)/right heart catheterization (RHC) method.

methodsProspective study of 70 clinically indicated patients referred for same-day CMR and RHC [60 ± 16 years; 77% females, 16 mPAP <25 mmHg (PVR <240 dynes.s.cm

resultsBaseline demographic characteristics were well matched. There was a significant difference in mPAP (P < 0.001), PVR (P = 0.001), and pulmonary Zc between mPAP<25 mmHg patients and those with PH (mPAP <25 mmHg: 47 ± 19 dynes.s.cm

conclusionsRaised pulmonary Zc was independent of elevated mPAP in patients with PH and more strongly predictive of maladaptive RV remodelling than PVR and mPAP. Use of this straightforward method to determine pulmonary Zc may help to better characterize pulsatile components of RV afterload in patients with PH than mPAP or PVR alone.

Indexed as

Hypertension, PulmonaryVentricular Dysfunction, RightElectric ImpedanceFemaleHumansMalePrognosisProspective StudiesCardiac magnetic resonance imagingPulmonary arterial impedanceRight heart catheterizationRight ventricular-pulmonary arterial coupling

Identifiers

PMID36896830
PMCPMC10192280
OpenAlexW4323807072

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.