Evidence map›Paper›PMID 36900271›Full record

ArticleCancers2023

CRP/Albumin Ratio and Glasgow Prognostic Score Provide Prognostic Information in Myelofibrosis Independently of MIPSS70-A Retrospective Study.

Nora-Medea Messerich, Narasimha Rao Uda, Thomas Volken, Sergio Cogliatti, Thomas Lehmann, Andreas Holbro, Rudolf Benz, Lukas Graf, Vikas Gupta, Wolfram Jochum and 3 more

Full text read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nora-Medea MesserichDepartment of Intensive Care, Cantonal Hospital St. Gallen, 9007 St. Gallen, Switzerland.
Narasimha Rao UdaLaboratory of Stem Cells and Cancer Biology, Department of Oncology and Hematology, Medical Research Center, Cantonal Hospital St. Gallen, 9007 St. Gallen, Switzerland.
Thomas VolkenZHAW School of Health Sciences, Institute of Public Health, 8400 Winterthur, Switzerland.ORCID 0000-0002-1490-011X
Sergio CogliattiInstitute of Pathology, Cantonal Hospital St. Gallen, 9007 St. Gallen, Switzerland.
Thomas LehmannInstitute of Pathology, Cantonal Hospital St. Gallen, 9007 St. Gallen, Switzerland.ORCID 0000-0002-5750-6876
Andreas HolbroDivision of Hematology, University Hospital of Basel, University of Basel, 4001 Basel, Switzerland.
Rudolf BenzDivision of Hematology and Oncology, Spital Thurgau AG, 8569 Muensterlingen, Switzerland.ORCID 0000-0001-8198-6454
Lukas GrafCentre for Laboratory Medicine, 9001 St. Gallen, Switzerland.ORCID 0000-0002-5556-4351
Vikas GuptaPrincess Margaret Cancer Center, University of Toronto, Toronto, ON M5S 1A1, Canada.
Wolfram JochumInstitute of Pathology, Cantonal Hospital St. Gallen, 9007 St. Gallen, Switzerland.ORCID 0000-0001-6170-2020
Izadora DemmerInstitute of Pathology, Cantonal Hospital St. Gallen, 9007 St. Gallen, Switzerland.
Tata Nageswara RaoLaboratory of Stem Cells and Cancer Biology, Department of Oncology and Hematology, Medical Research Center, Cantonal Hospital St. Gallen, 9007 St. Gallen, Switzerland.
Tobias SilzleClinic for Medical Oncology and Hematology, Cantonal Hospital St. Gallen, 9007 St. Gallen, Switzerland.ORCID 0000-0001-6859-3090

Funding

Novartis Foundation for medical-biological Research 20C223Research fund of the Cantonal Hospital St, Gallen 21.35Swiss Cancer League KLS-5158-08-2020Swiss National Science Foundation 320030_189090/1
6 · The paper itself

Abstract

In myelofibrosis, the C-reactive protein (CRP)/albumin ratio (CAR) and the Glasgow Prognostic Score (GPS) add prognostic information independently of the Dynamic International Prognostic Scoring System (DIPSS). Their prognostic impact, if molecular aberrations are considered, is currently unknown. We performed a retrospective chart review of 108 MF patients (prefibrotic MF n = 30; primary MF n = 56; secondary MF n = 22; median follow-up 42 months). In MF, both a CAR > 0.347 and a GPS > 0 were associated with a shorter median overall survival (21 [95% CI 0-62] vs. 80 months [95% CI 57-103],

Indexed as

albuminC-reactive proteinCRP/albumin ratioGlasgow Prognostic ScoreMIPSS70myelofibrosisprognostication

Identifiers

PMID36900271
PMCPMC10000567

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read60
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.