Evidence mapPaperPMID 36901695Full record

ArticleInternational journal of molecular sciences2023

Human Colonoid-Myofibroblast Coculture for Study of Apical Na

Azam Salari, Kunyan Zhou, Katerina Nikolovska, Ursula Seidler, Mahdi Amiri

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In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Ion transport and epithelial barrier dysfunction in experimental models of ulcerative colitis.American journal of physiology. Gastrointestinal and liver physiology · 2025
    Review
  3. Article
  4. The electroneutral NaAmerican journal of physiology. Cell physiology · 2024
    Article
  5. Article
  6. The Role of Ion-Transporting Proteins in Human Disease.International journal of molecular sciences · 2024
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Azam SalariDepartment of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.
Kunyan ZhouDepartment of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.
Katerina NikolovskaDepartment of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.
Ursula SeidlerDepartment of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0002-9600-2769
Mahdi AmiriDepartment of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0003-4775-9535

Funding

Deutsche Forschungsgemeinschaft Se460/21-1Deutsche Forschungsgemeinschaft Se460/22-1
6 · The paper itself

Abstract

Cation and anion transport in the colonocyte apical membrane is highly spatially organized along the cryptal axis. Because of lack of experimental accessibility, information about the functionality of ion transporters in the colonocyte apical membrane in the lower part of the crypt is scarce. The aim of this study was to establish an in vitro model of the colonic lower crypt compartment, which expresses the transit amplifying/progenitor (TA/PE) cells, with accessibility of the apical membrane for functional study of lower crypt-expressed Na

Indexed as

MyofibroblastsSodium-Hydrogen ExchangersCell MembraneCoculture TechniquesEpithelial CellsHumansHydrogen-Ion ConcentrationSodium-Hydrogen Exchangersclaudinscolonic electrolyte transporthuman intestinal organoidsintestinal barrierpHi regulationSLC9 familysodium–hydrogen exchange

Identifiers

PMID36901695
PMCPMC10001859

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read49
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.