Evidence map›Paper›PMID 36901728›Full record

ArticleInternational journal of molecular sciences2023

Analysis of the Localization of

Esther San-Quirico, M Ángeles Curto, Laura Gómez-Delgado, M Belén Moreno, Pilar Pérez, Juan Carlos Ribas, Juan Carlos G Cortés

Full text read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Esther San-QuiricoInstituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas (CSIC) and Universidad de Salamanca, 37007 Salamanca, Spain.
M Ángeles CurtoInstituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas (CSIC) and Universidad de Salamanca, 37007 Salamanca, Spain.
Laura Gómez-DelgadoInstituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas (CSIC) and Universidad de Salamanca, 37007 Salamanca, Spain.
M Belén MorenoInstituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas (CSIC) and Universidad de Salamanca, 37007 Salamanca, Spain.
Pilar PérezInstituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas (CSIC) and Universidad de Salamanca, 37007 Salamanca, Spain.
Juan Carlos RibasInstituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas (CSIC) and Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0001-6430-0895
Juan Carlos G CortésInstituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas (CSIC) and Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-2395-6668

Funding

Junta de Castilla y León, Spain and ERDF, EU CSI150P20Junta de Castilla y León, Spain and ERDF, EU "Escalera de Excelencia" CLU-2017-03Ministerio de Ciencia e Innovación, MCIN / AEI / 10.13039/501100011033, Spain and ERDF A way of making Europe, EU PGC2018-098924-B-I00Ministerio de Ciencia e Innovación, MCIN / AEI / 10.13039/501100011033, Spain and ERDF A way of making Europe, EU PID2021-124971NB-I00
6 · The paper itself

Abstract

In recent years, invasive fungal infections have emerged as a common source of infections in immunosuppressed patients. All fungal cells are surrounded by a cell wall that is essential for cell integrity and survival. It prevents cell death and lysis resulting from high internal turgor pressure. Since the cell wall is not present in animal cells, it is an ideal target for selective invasive fungal infection treatments. The antifungal family known as echinocandins, which specifically inhibit the synthesis of the cell wall β(13)glucan, has been established as an alternative treatment for mycoses. To explore the mechanism of action of these antifungals, we analyzed the cell morphology and glucan synthases localization in

Indexed as

SchizosaccharomycesSchizosaccharomyces pombe ProteinsAntifungal AgentsCaspofunginCell WallEchinocandinsGlucansGlucosyltransferasesAntifungal AgentsCaspofunginEchinocandinsGlucansGlucosyltransferasesSchizosaccharomyces pombe Proteinsantifungal resistanceantifungalscaspofungincell lysiscell wallcytokinesisechinocandinsfission yeastfungiglucangreen fluorescent proteininvasive mycosesyeastβ(1-3)glucan synthase

Identifiers

PMID36901728
PMCPMC10002279

What Socratic holds

Textfull text, public
LicenceCC BY
reference markers read4
measurements read66
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.