Evidence map›Paper›PMID 36901780›Full record

ArticleInternational journal of molecular sciences2023

Small Cellular Particles from European Spruce Needle Homogenate.

Marko Jeran, Anna Romolo, Vesna Spasovski, Matej Hočevar, Urban Novak, Roman Štukelj, Vid Šuštar, Matic Kisovec, Apolonija Bedina Zavec, Ksenija Kogej and 3 more

Full text read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marko JeranUniversity of Ljubljana, Laboratory of Clinical Biophysics, Faculty of Health Sciences, SI-1000 Ljubljana, Slovenia.ORCID 0000-0001-8064-4970
Anna RomoloUniversity of Ljubljana, Laboratory of Clinical Biophysics, Faculty of Health Sciences, SI-1000 Ljubljana, Slovenia.
Vesna SpasovskiUniversity of Ljubljana, Laboratory of Clinical Biophysics, Faculty of Health Sciences, SI-1000 Ljubljana, Slovenia.
Matej HočevarInstitute for Metals and Technology, SI-1000 Ljubljana, Slovenia.
Urban NovakTheory Department, National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.
Roman ŠtukeljUniversity of Ljubljana, Laboratory of Clinical Biophysics, Faculty of Health Sciences, SI-1000 Ljubljana, Slovenia.
Vid ŠuštarUniversity of Ljubljana, Laboratory of Clinical Biophysics, Faculty of Health Sciences, SI-1000 Ljubljana, Slovenia.
Matic KisovecDepartment of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.ORCID 0000-0003-4131-2177
Apolonija Bedina ZavecDepartment of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.
Ksenija KogejUniversity of Ljubljana, Faculty of Chemistry and Chemical Technology, SI-1000 Ljubljana, Slovenia.ORCID 0000-0002-6291-1032
Aleš IgličUniversity of Ljubljana, Laboratory of Physics, Faculty of Electrical Engineering, SI-1000 Ljubljana, Slovenia.ORCID 0000-0002-7895-343X
Polonca TrebšeUniversity of Ljubljana, Laboratory of Clinical Biophysics, Faculty of Health Sciences, SI-1000 Ljubljana, Slovenia.ORCID 0000-0003-4979-1336
Veronika Kralj-IgličUniversity of Ljubljana, Laboratory of Clinical Biophysics, Faculty of Health Sciences, SI-1000 Ljubljana, Slovenia.ORCID 0000-0002-7496-2005

Funding

Slovenian Research Agency P2-0232, P3-0388, P1-0201, P1-0391, J3-3066, L3-2621, J2-4447, IO-0003
6 · The paper itself

Abstract

Small cellular particles (SCPs) are being considered for their role in cell-to-cell communication. We harvested and characterized SCPs from spruce needle homogenate. SCPs were isolated by differential ultracentrifugation. They were imaged by scanning electron microscope (SEM) and cryogenic transmission electron microscope (cryo TEM), assessed for their number density and hydrodynamic diameter by interferometric light microscopy (ILM) and flow cytometry (FCM), total phenolic content (TPC) by UV-vis spectroscopy, and terpene content by gas chromatography-mass spectrometry (GC-MS). The supernatant after ultracentrifugation at 50,000×

Indexed as

PiceaFlow CytometryGas Chromatography-Mass SpectrometryMicroscopyTerpenesTerpenescell-to-cell communicationdrug deliveryexosomesextracellular particlesextracellular vesiclesinterferometric light microscopyPicea abiessmall cellular particlesspruce needles

Identifiers

PMID36901780
PMCPMC10001569

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read39
identifiers read3
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.