Evidence map›Paper›PMID 36902022›Full record

ArticleInternational journal of molecular sciences2023

Assessment of sST2 Behaviors to Evaluate Severity/Clinical Impact of Acute Pulmonary Embolism.

Luigi Petramala, Antonio Concistrè, Francesca Sarlo, Silvia Baroni, Marianna Suppa, Adriana Servello, Francesco Circosta, Gioacchino Galardo, Orietta Gandini, Luca Marino and 3 more

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In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Luigi PetramalaDepartment of Translational and Precision Medicine, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0003-4463-4956
Antonio ConcistrèDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, "Sapienza" University of Rome, 00185 Rome, Italy.
Francesca SarloUOC Chimica, Biochimica e Biologia Molecolare Clinica, Fondazione Policlinico Universitario A. Gemelli I.R.C.C.S., 00185 Rome, Italy.
Silvia BaroniUOC Chimica, Biochimica e Biologia Molecolare Clinica, Fondazione Policlinico Universitario A. Gemelli I.R.C.C.S., 00185 Rome, Italy.
Marianna SuppaEmergency Medicine Unit, Department of Emergency-Acceptance, Critical Areas and Trauma, Policlinico "Umberto I", 00185 Rome, Italy.
Adriana ServelloEmergency Medicine Unit, Department of Emergency-Acceptance, Critical Areas and Trauma, Policlinico "Umberto I", 00185 Rome, Italy.
Francesco CircostaDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, "Sapienza" University of Rome, 00185 Rome, Italy.
Gioacchino GalardoEmergency Medicine Unit, Department of Emergency-Acceptance, Critical Areas and Trauma, Policlinico "Umberto I", 00185 Rome, Italy.
Orietta GandiniDepartment of Molecular Medicine, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0002-7867-1010
Luca MarinoEmergency Medicine Unit, Department of Emergency-Acceptance, Critical Areas and Trauma, Policlinico "Umberto I", 00185 Rome, Italy.ORCID 0000-0001-7380-6222
Giuseppe CavallaroDepartment of Surgery Pietro Valdoni, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0001-7121-2295
Gino IannucciDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0003-3055-965X
Claudio LetiziaDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0003-4397-0624

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary embolism (PE) is a potentially life-threatening disorder. Beyond its usefulness in the prognostic stratification of heart failure, sST2 can represent a biomarker with high utility in several acute conditions. Our study was aimed to investigate whether sST2 can be used as a clinical marker of severity and prognostic outcome in acute PE. We enrolled 72 patients with documented PE and 38 healthy subjects; we measured the plasma concentrations of sST2 to evaluate the prognostic and severity performance of different levels of sST2 according to its association with the pulmonary embolism severity index (PESI) score and several parameters of respiratory function. PE patients had significantly higher levels of sST2 compared with healthy subjects (87.74 ± 17.1 vs. 17.1 ± 0.4 ng/mL,

Indexed as

Pulmonary EmbolismBiomarkersHumansLactatesBiomarkersLactatesprognostic biomarkerpulmonary thromboembolismseverity risk stratificationsoluble ST2

Identifiers

PMID36902022
PMCPMC10002919

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read40
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.