ReviewInternational journal of molecular sciences2023
The Impact of Aerobic Exercise on HDL Quantity and Quality: A Narrative Review.
Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06987708 (Evaluating the Impact of a 12-month Multi-Modal Lifestyle Management Intervention on Disease Relevant Biomarkers Associated With Monoclonal Gammopathy of Unknown Significance), which is not on this map. Cited by 79 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluating the Impact of a 12-month Multi-Modal Lifestyle Management Intervention on Disease Relevant Biomarkers Associated With Monoclonal Gammopathy of Unknown Significance (MGUS) and Smoldering Myeloma (SM): A Prospective Intervention Pilot Study
Who cites it
79 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Effects of high-intensity interval training on glycemic control and cardiometabolic risk factors in adults with prediabetes: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Physical activity interventions in adult kidney transplant recipients: an updated systematic review and meta-analysis of randomized controlled trials.Renal failure · 2025Pooled it
- Exploring the gut-exercise link: A systematic review of gastrointestinal disorders in physical activity.World journal of gastroenterology · 2025Pooled it
- Effects of physical exercise on the lipid profile of perimenopausal and postmenopausal women: a systematic review and meta-analysis.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025Pooled it
- Combined Effects of Physical Activity and Diet on Cancer Patients: A Systematic Review and Meta-Analysis.Nutrients · 2024Pooled it
- Does dance therapy benefit the improvement of blood pressure and blood lipid in patients with hypertension? A systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2024Pooled it
- Trial
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- The Role of Exercise-Based Cardiac Rehabilitation After Myocardial Infarction on Cholesterol Transfer to HDL.International journal of molecular sciences · 2025Trial
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- A Randomized Controlled Trial to Determine the Impact of Resistance Training versus Aerobic Training on the Management of FGF-21 and Related Physiological Variables in Obese Men with Type 2 Diabetes Mellitus.Journal of sports science & medicine · 2024Trial
- Twelve-Week Safety and Potential Lipid Control Efficacy of Coffee Cherry Pulp Juice Concentrate in Healthy Volunteers.Nutrients · 2023Trial
- Physical Activity Modifies the Association Between Atherogenic Index of Plasma and New-Onset Diabetes in Middle-Aged and Older Adults.Healthcare (Basel, Switzerland) · 2026Article
- Machine Learning Prediction Model for Dyslipidemia and Its Association With Atherothrombotic Events in 3 Independent Cohorts From South Korea, Japan, and the United Kingdom: Algorithm Development and Validation Study.JMIR medical informatics · 2026Article
- Effects of Maximal Fat Oxidation Exercise Training for Body Composition and Cardiovascular Risk Factors on College Students With Obesity.Reviews in cardiovascular medicine · 2026Article
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- Age-Dependent Differences in Exercise Response Among Healthy Women: Impact on Inflammation, Lipids Profile and Glucose.Biomedicines · 2026Article
- Characterization and response to exercise training of HDL-specific phospholipid efflux.Journal of lipid research · 2026Article
- Non-HDL Cholesterol and Residual Cardiometabolic Risk in Middle Eastern Patients with Atherosclerotic Cardiovascular Disease.Healthcare (Basel, Switzerland) · 2026Article
- Impact of a Longer-Term Physical Activity Intervention on Inflammatory and Oxidative Stress Biomarkers in Older People with Metabolic Syndrome.Antioxidants (Basel, Switzerland) · 2026Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High-density lipoproteins comprise roughly 25-30% of the circulating proteins involved in the transport of lipids in circulation. These particles differ in size and lipid composition. Recent evidence suggests that the quality of HDL particles (which depends on shape, size and the composition of proteins and lipids determining HDL functionality) may be more important than their quantity. The functionality of HDL is mirrored by its cholesterol efflux activity, as well as its antioxidant (including the protection of LDL against oxidation), anti-inflammatory and antithrombotic properties. The results of many studies and meta-analyses imply the beneficial impact of aerobic exercise on HDL-C levels. Physical activity was found to be usually associated with an increase in HDL cholesterol and a decrease in LDL cholesterol and triglycerides. Exercise, apart from inducing quantitative alterations in serum lipids, exerts a beneficial impact on HDL particle maturation, composition and functionality. The Physical Activity Guidelines Advisory Committee Report underlined the importance of establishing a program recommending exercises that enable attainment of maximal advantage at the lowest level of risk. The aim of this manuscript is to review the impact of different types of aerobic exercise (various intensities and durations) on the level and quality of HDL.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.