Evidence mapPaperPMID 36902824Full record

ArticleJournal of clinical medicine2023

The Impact of COVID-19 Pandemic Lockdown on the Relationship between Pediatric MAFLD and Renal Function.

Maria Sole Valentino, Pierluigi Marzuillo, Claudia Esposito, Mario Bartiromo, Michele Nardolillo, Annalisa Valentina Villani, Alessandro Maresca, Giuseppe Furcolo, Stefano Guarino, Emanuele Miraglia Del Giudice and 1 more

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Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maria Sole ValentinoDepartment of Woman, Child, and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0001-8445-1236
Pierluigi MarzuilloDepartment of Woman, Child, and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-4682-0170
Claudia EspositoDepartment of Woman, Child, and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Mario BartiromoDepartment of Woman, Child, and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Michele NardolilloDepartment of Woman, Child, and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Annalisa Valentina VillaniDepartment of Woman, Child, and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-2686-7940
Alessandro MarescaDepartment of Woman, Child, and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Giuseppe FurcoloUnità Operativa Complessa di Pediatria e Pronto Soccorso Pediatrico, AORN Moscati, 83100 Avellino, Italy.
Stefano GuarinoDepartment of Woman, Child, and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Emanuele Miraglia Del GiudiceDepartment of Woman, Child, and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Anna Di SessaDepartment of Woman, Child, and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-5877-3757

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBoth direct and indirect effects of COVID-19 have been found in all age groups. In particular, adult data demonstrated significant changes in patients with chronic and metabolic disease (e.g., obesity, diabetes, chronic kidney disease (CKD), and metabolic associated fatty liver dysfunction (MAFLD)), while similar pediatric evidence is still limited. We aimed at investigating the impact of the COVID-19 pandemic lockdown on the relationship between MAFLD and renal function in children with CKD due to congenital abnormalities of the kidney and urinary tract (CAKUT).

methodsA total of 21 children with CAKUT and CKD ≥ stage 1 underwent a comprehensive evaluation within 3 months before and 6 months after the first Italian lockdown.

resultsAt follow-up, CKD patients with MAFLD presented higher BMI-SDS, serum uric acid, triglycerides, and microalbuminuria levels and lower eGFR levels than those without MAFLD (all

conclusionsDue to the negative influence of the COVID-19 lockdown on cardiometabolic health in childhood, a careful management of children with CKD is warranted.

Indexed as

childrenchronic kidney diseaseCOVID-19lockdownmetabolic associated fatty liver diseaserenal function

Identifiers

PMID36902824
PMCPMC10003972

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.