Evidence map›Paper›PMID 36903471›Full record

ArticleMolecules (Basel, Switzerland)2023

It Takes Two to Tango, Part II: Synthesis of A-Ring Functionalised Quinones Containing Two Redox-Active Centres with Antitumour Activities.

Joyce C Oliveira, Renato L de Carvalho, Hugo G S Sampaio, João Honorato, Javier A Ellena, Felipe T Martins, João V M Pereira, Pedro M S Costa, Claudia Pessoa, Rafaela S Ferreira and 3 more

Full text read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Bioorganic Chemistry: Current and Future Perspectives.Molecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Joyce C OliveiraInstitute of Exact Sciences, Department of Chemistry, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.
Renato L de CarvalhoInstitute of Exact Sciences, Department of Chemistry, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.
Hugo G S SampaioInstitute of Exact Sciences, Department of Chemistry, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.
João HonoratoSão Carlos Institute of Physics, Physics and Interdisciplinary Sciences Department, Universidade de São Paulo, USP, São Carlos 13560-970, Brazil.ORCID 0000-0002-1127-6083
Javier A EllenaSão Carlos Institute of Physics, Physics and Interdisciplinary Sciences Department, Universidade de São Paulo, USP, São Carlos 13560-970, Brazil.ORCID 0000-0002-0676-3098
Felipe T MartinsChemistry Institute, Universidade Federal de Goiás, UFG, Goiânia 74690-900, Brazil.
João V M PereiraDepartment of Physiology and Pharmacology, Universidade Federal de Ceará, UFC, Fortaleza 60430-270, Brazil.
Pedro M S CostaDepartment of Physiology and Pharmacology, Universidade Federal de Ceará, UFC, Fortaleza 60430-270, Brazil.
Claudia PessoaDepartment of Physiology and Pharmacology, Universidade Federal de Ceará, UFC, Fortaleza 60430-270, Brazil.
Rafaela S FerreiraBiological Sciences Institute, Biochemistry and Immunology Department, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.ORCID 0000-0003-3324-0601
Maria H AraújoInstitute of Exact Sciences, Department of Chemistry, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.
Claus JacobDivision of Bioorganic Chemistry, School of Pharmacy, University of Saarland, 66123 Saarbruecken, Germany.ORCID 0000-0002-6288-7220
Eufrânio N da Silva JúniorInstitute of Exact Sciences, Department of Chemistry, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.ORCID 0000-0003-1281-5453

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2021, our research group published the prominent anticancer activity achieved through the successful combination of two redox centres (

Indexed as

NaphthoquinonesQuinonesAnimalsBenzoquinonesClick ChemistryCycloaddition ReactionMiceOxidation-ReductionBenzoquinonesNaphthoquinonesquinoneQuinonesanticancer activityclick chemistryquinonesredox centrestriazoles

Identifiers

PMID36903471
PMCPMC10005332

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read216
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.