Evidence map›Paper›PMID 36903531›Full record

ArticleMolecules (Basel, Switzerland)2023

DeepmRNALoc: A Novel Predictor of Eukaryotic mRNA Subcellular Localization Based on Deep Learning.

Shihang Wang, Zhehan Shen, Taigang Liu, Wei Long, Linhua Jiang, Sihua Peng

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Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. lncRNA localization and feature interpretability analysis.Molecular therapy. Nucleic acids · 2025
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shihang WangSchool of Information Engineering, Huzhou University, Huzhou 313000, China.ORCID 0000-0002-4714-6504
Zhehan ShenDepartment of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Taigang LiuCollege of Information Technology, Shanghai Ocean University, Shanghai 201306, China.ORCID 0000-0002-8449-9667
Wei LongSchool of Information Engineering, Huzhou University, Huzhou 313000, China.
Linhua JiangSchool of Information Engineering, Huzhou University, Huzhou 313000, China.
Sihua PengSchool of Information Engineering, Huzhou University, Huzhou 313000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The subcellular localization of messenger RNA (mRNA) precisely controls where protein products are synthesized and where they function. However, obtaining an mRNA's subcellular localization through wet-lab experiments is time-consuming and expensive, and many existing mRNA subcellular localization prediction algorithms need to be improved. In this study, a deep neural network-based eukaryotic mRNA subcellular location prediction method, DeepmRNALoc, was proposed, utilizing a two-stage feature extraction strategy that featured bimodal information splitting and fusing for the first stage and a VGGNet-like CNN module for the second stage. The five-fold cross-validation accuracies of DeepmRNALoc in the cytoplasm, endoplasmic reticulum, extracellular region, mitochondria, and nucleus were 0.895, 0.594, 0.308, 0.944, and 0.865, respectively, demonstrating that it outperforms existing models and techniques.

Indexed as

Deep LearningEukaryotaComputational BiologyEndoplasmic ReticulumProteinsRNA, MessengerProteinsRNA, Messengerartificial intelligencechaos-game representationdeep learningmRNA subcellular localization

Identifiers

PMID36903531
PMCPMC10005629

What Socratic holds

Textfull text, public
LicenceCC BY
reference markers read3
measurements read5
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.