Evidence map›Paper›PMID 36903613›Full record

ArticleMolecules (Basel, Switzerland)2023

The Protective Effect of (-)-Tetrahydroalstonine against OGD/R-Induced Neuronal Injury via Autophagy Regulation.

Yumei Liao, Jun-Ya Wang, Yan Pan, Xueyi Zou, Chaoqun Wang, Yinghui Peng, Yun-Lin Ao, Mei Fong Lam, Xiaoshen Zhang, Xiao-Qi Zhang and 2 more

Full text read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yumei LiaoDepartment of Cardiovascular Surgery, The First Affiliated Hospital, Jinan University, Guangzhou 510632, China.
Jun-Ya WangGuangdong Provincial Engineering Research Center for Modernization of TCM, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Yan PanJNU-HKUST Joint Laboratory for Neuroscience and Innovative Drug Research, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Xueyi ZouJNU-HKUST Joint Laboratory for Neuroscience and Innovative Drug Research, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Chaoqun WangJNU-HKUST Joint Laboratory for Neuroscience and Innovative Drug Research, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Yinghui PengJNU-HKUST Joint Laboratory for Neuroscience and Innovative Drug Research, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Yun-Lin AoGuangdong Provincial Engineering Research Center for Modernization of TCM, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Mei Fong LamCentro Hospitalar Conde de São Januário, Macau, China.
Xiaoshen ZhangDepartment of Cardiovascular Surgery, The First Affiliated Hospital, Jinan University, Guangzhou 510632, China.
Xiao-Qi ZhangGuangdong Provincial Engineering Research Center for Modernization of TCM, College of Pharmacy, Jinan University, Guangzhou 510632, China.ORCID 0000-0002-4436-0273
Lei ShiDepartment of Cardiovascular Surgery, The First Affiliated Hospital, Jinan University, Guangzhou 510632, China.ORCID 0000-0001-8695-3432
Shiqing ZhangJNU-HKUST Joint Laboratory for Neuroscience and Innovative Drug Research, College of Pharmacy, Jinan University, Guangzhou 510632, China.ORCID 0000-0002-0785-5461

Funding

Key-Area Research and Development Program of Guangdong Province 2019B030335001National Natural Science Foundation of China U1801287, 82073712, 82071535, 82101614National Science and Technology Innovation 2030 Major Projects for "Brain Science and Brain-Inspired Research" 2022ZD0214400
6 · The paper itself

Abstract

Here, (-)-Tetrahydroalstonine (THA) was isolated from

Indexed as

Neuroprotective AgentsReperfusion InjuryApoptosisAutophagyGlucoseHumansNeuronsOxygenProto-Oncogene Proteins c-aktSecologanin Tryptamine AlkaloidsTOR Serine-Threonine KinasesGlucoseNeuroprotective AgentsOxygenProto-Oncogene Proteins c-aktraubasineSecologanin Tryptamine AlkaloidsTOR Serine-Threonine KinasesAkt/mTORautophagycerebral ischemiaOGD/R(-)-Tetrahydroalstonine

Identifiers

PMID36903613
PMCPMC10005631

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read28
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.