Evidence mapPaperPMID 36904249Full record

ArticleNutrients2023

Effect of Immuno-Nutrition on Malnutrition, Inflammatory Response and Clinical Course of Semi-Critically Ill COVID-19 Patients: A Pilot Perspective Study.

Marialaura Scarcella, Emidio Scarpellini, Sara Piergallini, Emanuele Rinninella, Karen Routhiaux, Carlo Rasetti, Ludovico Abenavoli, Edoardo De Robertis, Pietro Manzi, Rita Commissari and 2 more

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Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marialaura ScarcellaAnesthesia, Intensive Care and Nutritional Science-Azienda Ospedaliera "Santa Maria", Via Tristano di Joannuccio, 05100 Terni, Italy.
Emidio ScarpelliniClinical Nutrition Unit and Internal Medicine Unit, "Madonna del Soccorso" General Hospital, Via Luciano Manara 7, 63074 San Benedetto del Tronto, Italy.ORCID 0000-0002-2101-1118
Sara PiergalliniClinical Nutrition Unit and Internal Medicine Unit, "Madonna del Soccorso" General Hospital, Via Luciano Manara 7, 63074 San Benedetto del Tronto, Italy.
Emanuele RinninellaDepartment of Translational Medicine and Surgery, Clinical Nutrition Unit, Catholic University of Sacred Heart, Gemelli Foundation, 00168 Rome, Italy.ORCID 0000-0002-9165-2367
Karen RouthiauxTranslational Research Center for Gastrointestinal Disease (T.A.R.G.I.D.), Gasthuisberg University Hospital, KULeuven, Herestraat 49, 3000 Lueven, Belgium.
Carlo RasettiClinical Nutrition Unit and Internal Medicine Unit, "Madonna del Soccorso" General Hospital, Via Luciano Manara 7, 63074 San Benedetto del Tronto, Italy.
Ludovico AbenavoliDepartment of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy.ORCID 0000-0002-5922-1524
Edoardo De RobertisDivision of Anaesthesia, Analgesia, and Intensive Care - Department of Medicine and Surgery-University of Perugia, 06121 Perugia, Italy.ORCID 0000-0001-9182-6964
Pietro ManziAzienda Ospedaliera Santa Maria di Terni, 05100 Terni, Italy.
Rita CommissariAnesthesia and Intensive Care Azienda Ospedaliera Santa Maria Terni, 05100 Terni, Italy.
Riccardo MontiCardiologic and Pediatric Intensive Care Unit, 05100 Terni, Italy.
Michela ZanettiDepartment of Medical and Surgical Sciences, Azienda Sanitaria Universitaria "Giuliano-Isontina", Trieste University, 34148 Trieste, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe SARS-COV 2 pandemic has hit on our lives since early 2020. During different contagion waves, both malnutrition and overweight significantly correlated with patient mortality. Immune-nutrition (IN) has shown promising results in the clinical course of pediatric inflammatory bowel disease (IBD) and in both the rate of extubation and mortality of patients admitted to an intensive care unit (ICU). Thus, we wanted to assess the effects of IN on a clinical course of patients admitted to a semi-intensive COVID-19 Unit during the fourth wave of contagion that occurred at the end of 2021.

methodswe prospectively enrolled patients admitted to the semi-intensive COVID-19 Unit of San Benedetto General hospital. All patients had a biochemical, anthropometric, high-resolution tomography chest scan (HRCT) and complete nutritional assessments at the time of admission, after oral administration of immune-nutrition (IN) formula, and at 15 days interval follow-up.

resultswe enrolled 34 consecutive patients (age 70.3 ± 5.4 years, 6 F, BMI 27.0 ± 0.5 kg/m

conclusionsin this overweight COVID-19 population immune-nutrition prevented malnutrition development with a significant decrease of inflammatory markers.

Indexed as

COVID-19MalnutritionAgedAged, 80 and overChildCritical IllnessDisease ProgressionHumansImmunonutrition DietMiddle AgedNutrition AssessmentOverweightCOVID-19immune-nutritioninflammationmalnutritionover-weightsemi-intensive care

Identifiers

PMID36904249
PMCPMC10004815

What Socratic holds

Textfull text, public
LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.