Evidence map›Paper›PMID 36904447›Full record

ArticlePolymers2023

Combination of Cellulose Derivatives and Chitosan-Based Polymers to Investigate the Effect of Permeation Enhancers Added to In Situ Nasal Gels for the Controlled Release of Loratadine and Chlorpheniramine.

Prasanth Viswanadhan Vasantha, Sheri Peedikayil Sherafudeen, Mohamed Rahamathulla, Sam Thomarayil Mathew, Sandhya Murali, Sultan Alshehri, Faiyaz Shakeel, Prawez Alam, Ala Yahya Sirhan, Bhageerathy Anantha Narayana Iyer

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In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Chitosan Biomaterials: Advances and Challenges.International journal of molecular sciences · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Prasanth Viswanadhan VasanthaDepartment of Pharmaceutics, Mount Zion College of Pharmaceutical Sciences and Research, Chayalode P.O. Ezhamkulam, Pathanamthitta Dist, Adoor 691556, India.
Sheri Peedikayil SherafudeenDepartment of Pharmaceutics, Mar Discorous College of Pharmacy, Alathara, Sreekariyam, Thiruvananthapuram Dist, Thiruvananthapuram 695017, India.
Mohamed RahamathullaDepartment of Pharmaceutics, College of Pharmacy, King Khalid University, Al Faraa, P.O. Box 62223, Abha 61421, Saudi Arabia.ORCID 0000-0001-8826-3718
Sam Thomarayil MathewResearcher and Medical Communication Expert, Bangalore 560076, India.
Sandhya MuraliDepartment of Pharmaceutics, Mount Zion College of Pharmaceutical Sciences and Research, Chayalode P.O. Ezhamkulam, Pathanamthitta Dist, Adoor 691556, India.
Sultan AlshehriDepartment of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Ad Diriyah 13713, Saudi Arabia.
Faiyaz ShakeelDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-6109-0885
Prawez AlamDepartment of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.ORCID 0000-0002-7632-3426
Ala Yahya SirhanFaculty of Pharmacy, Amman Arab University, Amman 11953, Jordan.
Bhageerathy Anantha Narayana IyerDepartment of Pharmaceutics, Mount Zion College of Pharmaceutical Sciences and Research, Chayalode P.O. Ezhamkulam, Pathanamthitta Dist, Adoor 691556, India.

Funding

Deanship of Scientific Research at King Khalid University, Saudi Arabia Large Program (grant number RGP-2/251/43)
6 · The paper itself

Abstract

The purpose of the study is to develop and assess mucoadhesive in situ nasal gel formulations of loratadine and chlorpheniramine maleate to advance the bioavailability of the drug as compared to its conventional dosage forms. The influence of various permeation enhancers, such as EDTA (0.2%

Indexed as

chitosanchlorpheniramineenhancement ratioloratadinepermeability coefficientpermeation enhancersteady state flux

Identifiers

PMID36904447
PMCPMC10006938

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read47
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.