Evidence map›Paper›PMID 36905403›Full record

ArticleMolecular biology reports2023

Myricetin-induced suicidal erythrocyte death.

Jibin Liu, Abdulla Al Mamun Bhuyan, Ke Ma, Xuexue Zhu, Kuo Zhou, Florian Lang

Abstract read
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In one paragraph

Article in Molecular biology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Jibin Liu *College of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, 1166 Liutai Avenue, Wenjiang, Chengdu, 611137, People's Republic of China.ORCID http://orcid.org/0000-0002-9925-0493
Abdulla Al Mamun Bhuyan *Department of Physiology, Eberhard-Karls-University of Tuebingen, Wilhlmstr. 56, 72076, Tuebingen, Germany.
Ke MaDepartment of Physiology, Eberhard-Karls-University of Tuebingen, Wilhlmstr. 56, 72076, Tuebingen, Germany.
Xuexue ZhuDepartment of Physiology, Eberhard-Karls-University of Tuebingen, Wilhlmstr. 56, 72076, Tuebingen, Germany.
Kuo ZhouDepartment of Physiology, Eberhard-Karls-University of Tuebingen, Wilhlmstr. 56, 72076, Tuebingen, Germany.
Florian LangDepartment of Physiology, Eberhard-Karls-University of Tuebingen, Wilhlmstr. 56, 72076, Tuebingen, Germany. florian.lang@uni-tuebingen.de.
University of Tübingen · DEChengdu University of Traditional Chinese Medicine · CN

Funding

Postdoctoral Research Foundation of China 2021MD703799
6 · The paper itself

Abstract

backgroundMyricetin, a type of flavonol commonly found in fruits and herbs, has demonstrated anticancer properties by triggering the process of apoptosis or programmed cell death in tumor cells. Despite the absence of mitochondria and nuclei, erythrocytes can undergo programmed cell death, also known as eryptosis.This process is characterized by cell shrinkage, externalization of phosphatidylserine (PS) on the cell membrane, and the formation of membrane blebs. The signaling of eryptosis involves Ca METHODS AND

resultsHuman erythrocytes were exposed to various concentrations of myricetin (2-8 µM) for 24 h. Flow cytometry was used to assess the markers of eryptosis, including PS exposure, cellular volume, cytosolic Ca

conclusionMyricetin triggers eryptosis, which is accompanied and, at least in part, caused by Ca

Indexed as

EryptosisAnnexinsCalciumCell SizeCeramidesErythrocytesFlavonoidsHemolysisHumansOxidative StressPhosphatidylserinesReactive Oxygen SpeciesAnnexinsCalciumCeramidesFlavonoidsmyricetinPhosphatidylserinesReactive Oxygen SpeciesCalciumCeramideEryptosisMyricetinOxidative stressPhosphatidylserine exposure

Identifiers

PMID36905403
OpenAlexW4323920681

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.