ArticleEuropean journal of nutrition2023
The association between adherence to a plant-based diet and cognitive ageing.
Article in European journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00696514 (Vitamin B12 and Folic Acid Supplementation for Preventing Fractures in Elderly People), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Vitamin B12 and Folic Acid Supplementation for Preventing Fractures in Elderly People
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Association between plant-based diets and incident dementia: results from prospective cohort studies and a meta-analysis.The journal of prevention of Alzheimer's disease · 2026Pooled it
- Plant-Based Diets and Cognitive Outcomes: A Systematic Review and Meta-analysis.Advances in nutrition (Bethesda, Md.) · 2025Pooled it
- Sustainable nutrition and mental health in older adults: the interplay of DASH diet quality, sustainable consumption behavior, cognitive function, and depression.BMC geriatrics · 2026Article
- Relative validity of an online short FFQ assessing the Dutch adapted version of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet in older adults at risk of cognitive decline.The British journal of nutrition · 2026Article
- EAT-Lancet and plant-based diets, plasma metabolomic signatures, and biological aging.npj aging · 2025Article
- Impact of Diverse Dietary Patterns on Cognitive Health: Cumulative Evidence from Prospective Cohort Studies.Nutrients · 2025Review
- The proportion of plant-based food consumption during midlife and cognitive health in later life in Australian women: data from the Women's Healthy Ageing Project (WHAP).European journal of nutrition · 2025Article
- The association between total, animal-based, and plant-based protein intake and cognitive decline in older adults.European journal of nutrition · 2025Article
- Interaction between living conditions and plant-based dietary pattern on cognitive function: A 10-year cohort analysis of Chinese older adults.The journal of nutrition, health & aging · 2025Article
- Adherence to the planetary health diet is associated with slower cognitive decline: a prospective cohort analysis of Chinese older adults.The international journal of behavioral nutrition and physical activity · 2025Article
- Association of Plant-Based Dietary Patterns with Activities of Daily Living Disability in Older Adults Based on a 10-Year Cohort Study.Nutrients · 2024Article
- A plant-based diet index to study the relation between diet and disease risk among adults: a narrative review.The journal of nutrition, health & aging · 2024Review
- The association between adherence to the EAT-Lancet diet and cognitive ageing.Age and ageing · 2024Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
purposeWhile the benefits of adopting a more plant-based diet for sustainability and animal welfare are clear, its long-term health impacts, including the impact on cognitive ageing, are limited studied. Therefore, we investigated the associations between plant-based diet adherence and cognitive ageing.
methodsData from a previous intervention study involving community-dwelling adults aged ≥ 65 years were analysed at baseline (n = 658) and after 2-year follow-up (n = 314). Global and domain-specific cognitive functioning were assessed at both timepoints. Overall, healthful and unhealthful plant-based dietary indices were calculated from a 190-item food frequency questionnaire. Multivariate-adjusted linear regression models were applied to test for associations.
resultsAfter full-adjustment, higher overall adherence to a plant-based diet was not associated with global cognitive function (difference in Z-score, tertile 1 versus 3 [95% CI]: 0.04 [- 0.05, 0.13] p = 0.40) or cognitive change (- 0.04 [- 0.11, 0.04], p = 0.35). Similarly, healthful and unhealthful plant-based diet indices were not associated with cognitive functioning (respectively p = 0.48; p = 0.87) or change (respectively p = 0.21, p = 0.33). Interestingly, we observed fish consumption to influence the association between plant-based diet adherence and cognitive functioning (p-interaction = 0.01), with only individuals with a fish consumption of ≥ 0.93 portion/week benefitting from better overall plant-based diet adherence (β per 10-point increment [95% CI]: 0.12 [0.03, 0.21] p = 0.01).
conclusionWe did not demonstrate associations of a more plant-based diet with cognitive ageing. However, possibly such association exists in a subpopulation with higher fish intake. This would be in line with earlier observations that diets rich in plant foods and fish, such as the Mediterranean diet, may be beneficial for cognitive ageing.
trial registrationRegistered at clinicaltrials.gov (NCT00696514) on June 12, 2008.
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