Evidence map›Paper›PMID 36907593›Full record

ArticleKorean journal of radiology2023

Assessing Cerebral Oxygen Metabolism Changes in Patients With Preeclampsia Using Voxel-Based Morphometry of Oxygen Extraction Fraction Maps in Magnetic Resonance Imaging.

Qihao Zhang, Chaofan Sui, Junghun Cho, Linfeng Yang, Tao Chen, Bin Guo, Kelly McCabe Gillen, Jing Li, Lingfei Guo, Yi Wang

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  5. Article
  6. Sensitivity assessment of QSM+qBOLD (or QQ) in detecting elevated oxygen extraction fraction (OEF) in physiological change.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Qihao Zhang *Department of Radiology, Weill Cornell Medical College, New York, NY, USA.ORCID 0000-0002-8054-5849
Chaofan Sui *Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.ORCID 0000-0002-1049-3772
Junghun ChoDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, New York, NY, USA.ORCID 0000-0002-0826-5463
Linfeng YangDepartment of Radiology, Jinan Maternity and Child Care Hospital, Jinan, Shandong, China.ORCID 0000-0002-3228-6926
Tao ChenDepartment of Clinical Laboratory, Jinan Maternity and Child Care Hospital, Jinan, Shandong, China.ORCID 0000-0002-0104-0608
Bin GuoDepartment of Radiology, Jinan Maternity and Child Care Hospital, Jinan, Shandong, China.ORCID 0000-0002-8867-2535
Kelly McCabe GillenDepartment of Radiology, Weill Cornell Medical College, New York, NY, USA.ORCID 0000-0003-1319-4900
Jing LiDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China. lijingxbhtr@163.com.ORCID 0000-0001-9392-6600
Lingfei GuoDepartment of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China. glfsci@163.com.ORCID 0000-0002-4885-625X
Yi WangDepartment of Radiology, Weill Cornell Medical College, New York, NY, USA.ORCID 0000-0003-1404-8526
Cornell University · USJinan Maternity And Care Hospital · CNShandong Provincial Hospital · CNCapital Medical University · CNUniversity at Buffalo, State University of New York · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of this study was to analyze the different brain oxygen metabolism statuses in preeclampsia using magnetic resonance imaging and investigate the factors that affect cerebral oxygen metabolism in preeclampsia. MATERIALS AND

methodsForty-nine women with preeclampsia (mean age 32.4 years; range, 18-44 years), 22 pregnant healthy controls (PHCs) (mean age 30.7 years; range, 23-40 years), and 40 non-pregnant healthy controls (NPHCs) (mean age 32.5 years; range, 20-42 years) were included in this study. Brain oxygen extraction fraction (OEF) values were computed using quantitative susceptibility mapping (QSM) plus quantitative blood oxygen level-dependent magnitude-based OEF mapping (QSM + quantitative blood oxygen level-dependent imaging or QQ) obtained with a 1.5-T scanner. Voxel-based morphometry (VBM) was used to investigate the differences in OEF values in the brain regions among the groups.

resultsAmong the three groups, the average OEF values were significantly different in multiple brain areas, including the parahippocampus, multiple gyri of the frontal lobe, calcarine, cuneus, and precuneus (all

conclusionUsing whole-brain VBM analysis, we found that patients with preeclampsia had higher OEF values than controls.

Indexed as

OxygenPre-EclampsiaAdultBrainBrain MappingCerebrovascular CirculationFemaleHumansMagnetic Resonance ImagingPregnancyOxygenCerebral hypoxiaMagnetic resonance imagingOxygen extraction fractionPreeclampsiaVoxel-based morphometry

Identifiers

PMID36907593
PMCPMC10067693
OpenAlexW4324009096

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.