Evidence map›Paper›PMID 36907918›Full record

ArticleIrish journal of medical science2023

Diagnostic value of pseudocapsule ring hyperenhancement in contrast-enhanced ultrasound in renal focal lesions.

Ligang Wang, Hao Wu, Jianchun Li, Ying Wang, Tingting Zhang, Zhaowang Tan, Yang Liu, Han Wang, Litao Sun, Dong Xu and 1 more

Abstract read
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In one paragraph

Article in Irish journal of medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Ligang WangCancer Center, Department of Ultrasound Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Zhejiang Province, Hangzhou, 310000, People's Republic of China.
Hao WuDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Zhejiang Province, Hangzhou, 310000, People's Republic of China.
Jianchun LiCancer Center, Department of Ultrasound Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Zhejiang Province, Hangzhou, 310000, People's Republic of China.
Ying WangHealth Management Center, Health Promotion Center, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Zhejiang Province, Hangzhou, 310000, People's Republic of China.
Tingting ZhangBengbu Medical College, Anhui Province, 230030, Bengbu, People's Republic of China.
Zhaowang TanBengbu Medical College, Anhui Province, 230030, Bengbu, People's Republic of China.
Yang LiuCancer Center, Department of Ultrasound Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Zhejiang Province, Hangzhou, 310000, People's Republic of China.
Han WangUltrasound Department, Zhejiang Hospital affiliated to Zhejiang, University School of Medicine, Zhejiang Province, Hangzhou, 310013, People's Republic of China.
Litao SunCancer Center, Department of Ultrasound Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Zhejiang Province, Hangzhou, 310000, People's Republic of China. Litaosun1971@sina.com.
Dong XuDepartment of Ultrasound Medicine, Cancer HospitalAffiliated to, University of Chinese Academy of Sciences (Zhejiang Cancer Hospital) , Zhejiang Province, Hangzhou, 310000, People's Republic of China. xudong@zjcc.org.cn.
Jianfeng TuEmergency and Critical Care Center, Department of Emergency Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Zhejiang Province, Hangzhou, 310000, People's Republic of China. ZRY-AP@hotmail.com.
Hangzhou Medical College · CNZhejiang Provincial People's Hospital · CNBengbu Medical College · CNZhejiang Cancer Hospital · CNZhejiang Chinese Medical University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectTo investigate the diagnostic value of pseudocapsule ring hyperenhancement in contrast-enhanced ultrasound (CEUS) of focal renal lesions.

methodNinety eligible patients admitted were selected as the study subjects. The incidence rate of annular hyperenhancement in different benign and malignant focal lesions during angiography and the shape of annular enhancement were counted. The correlation between the occurrence of benign and malignant renal tumors and annular hyperenhancement and unenhanced areas was also analyzed.

resultsCapsule enhancement was observed in 56 cases, including 50 cases of malignant tumors (89.3%, 50/56) and 6 cases of benign tumors (10.7%, 6/56). Pearson correlation analysis showed that renal malignancy was positively associated with the occurrence of pseudocapsule ring hyperenhancement (γ = 0.489, P < 0.001). Benign and malignant renal tumors were positively correlated with the occurrence of non-enhancing areas (γ = 0.215, P = 0.042). The thickness and peak intensity of pseudocapsule ring enhancement in renal malignant tumors were significantly higher than those in benign tumors (all P < 0.001), while the time to peak was significantly lower than that in benign tumors (P < 0.001). The results of receiver operating characteristic (ROC) curve showed that the ring enhancement thickness, time to peak, and area under ROC curve of peak intensity of tumor reached more than 0.9.

conclusionIn CEUS, the pseudocapsule of focal renal lesions is a characteristic feature of renal malignant tumors, which can be used as a differential basis for benign and malignant tumors to improve the accuracy of benign and malignant renal tumors.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsContrast MediaDiagnosis, DifferentialHumansKidneyROC CurveUltrasonographyContrast MediaCalcificationContrast-enhanced ultrasoundNo enhancement areaPseudocapsule annular hyperenhancementRenal tumor

Identifiers

PMID36907918
OpenAlexW4323981454

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.