Evidence map›Paper›PMID 36908768›Full record

ArticleResearch and practice in thrombosis and haemostasis2023

Platelet function studies in myeloproliferative neoplasms patients with

Alexandre Guy, Khalil Helzy, Olivier Mansier, Jean-Claude Bordet, Etienne Rivière, Mathieu Fiore, Chloe James

Abstract read
In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. [Emphasis on the etiological diagnosis and management of non-cirrhotic portal hypertension].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Acquired platelet disorders.Frontiers in medicine · 2025
    Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexandre GuyLaboratory of Hematology, University Hospital, Bordeaux, France.
Khalil HelzyLaboratory of Hematology, University Hospital, Bordeaux, France.
Olivier MansierLaboratory of Hematology, University Hospital, Bordeaux, France.
Jean-Claude BordetLaboratory of Hematology, University Hospital of Lyon, Bron, France.
Etienne RivièreInternal Medicine and Infectious Diseases Unit, University Hospital, Bordeaux, France.
Mathieu FioreLaboratory of Hematology, University Hospital, Bordeaux, France.
Chloe JamesLaboratory of Hematology, University Hospital, Bordeaux, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Objectives: Our main objective was to explore and compare platelet function depending on the MPN molecular marker. Methods: We analyzed platelet function in 16 patients with MPN with Results: We observed significant defects in platelet aggregation, surface glycoprotein expression, fibrinogen binding, and granule content in platelets from patients with MPN compared with that in controls. Moreover, soluble CD40L and P-selectin levels were elevated in patients with MPN compared with that in controls, suggesting an Conclusions: These results do not support the hypothesis that calreticulin-mutated platelets have platelet function defects that could explain the lower thrombotic risk of patients with

Indexed as

blood plateletscalreticulinJAK2V617F mutationmyeloproliferative neoplasmsplatelet aggregationthrombosis

Identifiers

PMID36908768
PMCPMC9992751

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.