ArticleFrontiers in nutrition2023
The correlation of muscle quantity and quality between all vertebra levels and level L3, measured with CT: An exploratory study.
Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- From neck to abdomen: cervical (C3) muscle quantification as a surrogate to lumbar (L3) sarcopenia assessment in head and neck cancer: systematic review and meta-analysis.Skeletal radiology · 2026Pooled it
- CT-derived myosteatosis as a predictor of postoperative outcomes in esophagogastric cancer surgery: a systematic review.Frontiers in medicine · 2026Pooled it
- Article
- Going beyond total skeletal muscle area at L3 (tSMA) to accurately assess pancreatic cancer cachexia.Journal of gastrointestinal oncology · 2026Article
- Technical performance of L3 skeletal muscle area (SMA) measurement on CT for L3 skeletal muscle index (L3SMI) assessment.Scientific reports · 2026Article
- Temporal change in skeletal muscle index as a predictor of recurrence for patients with locally advanced colorectal malignancy: a retrospective cohort study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Article
- Sarcopenia, myosteatosis and systemic immunoinflammatory index in the prediction of survival in patients undergoing immunotherapy for esophageal cancer.Scientific reports · 2026Article
- Evaluating objective nutritional biomarkers for the prediction of sarcopenia in Crohn's disease: development and internal validation of a clinical nomogram.Frontiers in nutrition · 2026Article
- Multimodal AI Model for Sarcopenia Detection: Integrating Chest CT and Clinical Parameters in Older Adults.Clinical interventions in aging · 2026Article
- Machine learning survival prediction in esophageal cancer using radiomics and body composition from pretreatment and follow-up T12-level computed tomography.World journal of gastrointestinal oncology · 2025Article
- Sarcopenia in rheumatic and musculoskeletal diseases: pathophysiology, diagnosis, and management.Rheumatology international · 2025Review
- Whole-Body [Scientific data · 2025Article
- Peripheral Thyroid Hormones, Inflammatory and Skeletal Muscle Indexes in Advanced Cervical Cancer Treated With Cemiplimab.Journal of cachexia, sarcopenia and muscle · 2025Article
- The value of unsupervised machine learning algorithms based on CT and MRI for predicting sarcopenia.Frontiers in public health · 2025Article
- Myosteatosis: diagnostic significance and assessment by imaging approaches.Quantitative imaging in medicine and surgery · 2024Review
- Comparison of different 2D muscle indexes measured at the level of the 3rd lumbar vertebra in survival prediction in patients with renal cell carcinoma.Acta oncologica (Stockholm, Sweden) · 2024Article
- Overall survival and short-term efficacy analysis of cervical squamous cell carcinoma with skeletal muscle andScientific reports · 2024Article
- Article
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Authors and funding
6 authors.
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Abstract
Introduction: In patients with cancer, low muscle mass has been associated with a higher risk of fatigue, poorer treatment outcomes, and mortality. To determine body composition with computed tomography (CT), measuring the muscle quantity at the level of lumbar 3 (L3) is suggested. However, in patients with cancer, CT imaging of the L3 level is not always available. Thus far, little is known about the extent to which other vertebra levels could be useful for measuring muscle status. In this study, we aimed to assess the correlation of the muscle quantity and quality between any vertebra level and L3 level in patients with various tumor localizations. Methods: Two hundred-twenty Positron Emission Tomography (PET)-CT images of patients with four different tumor localizations were included: 1. head and neck ( Results: For SMA, strong correlations were found between C1-C3 and L3, and C7-L5 and L3 ( Discussion: For muscle quantity, the correlations between the cervical, thoracic, and lumbar levels are good, except for the cervical levels in patients with esophageal cancer. For muscle quality, the correlations between the other levels and L3 are good, except for the cervical levels in patients with melanoma. If visualization of L3 on the CT scan is absent, the other thoracic and lumbar vertebra levels could serve as a proxy to measure muscle quantity and quality in patients with head and neck, esophageal, lung cancer, and melanoma, whereas the cervical levels may be less reliable as a proxy in some patient groups.
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