Evidence map›Paper›PMID 36909653›Full record

ArticlebioRxiv : the preprint server for biology2023

A live-cell platform to isolate phenotypically defined subpopulations for spatial multi-omic profiling.

Tala O Khatib, Angelica M Amanso, Brian Pedro, Christina M Knippler, Emily R Summerbell, Najdat M Zohbi, Jessica M Konen, Janna K Mouw, Adam I Marcus

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Tala O KhatibDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, Georgia, USA.
Angelica M AmansoDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, Georgia, USA.
Brian PedroDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Christina M KnipplerDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, Georgia, USA.
Emily R SummerbellOffice of Intratumoral Training and Education, The National Institutes of Health, Bethesda, Maryland, USA.
Najdat M ZohbiGraduate Medical Education, Piedmont Macon Medical, Macon, Georgia, USA.
Jessica M KonenDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, Georgia, USA.
Janna K MouwDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, Georgia, USA.
Adam I MarcusDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, Georgia, USA.
Emory University · USJohns Hopkins University · USNational Institutes of Health · USNavicent Health · US

Funding

Winship Cancer Institute Cancer Center Support GrantP30CA138292 · NCI · EMORY UNIVERSITY · PI Suresh S Ramalingam · 2009 to 2026
$47.5M
Spatiotemporal interrogation of metabolic cooperation between heterogenous lung cancer subpopulations in collective cell invasionR01CA247367 · NCI · EMORY UNIVERSITY · PI MARCUS, ADAM I., SHANMUGAM, MALATHY (MALA) · 2021 to 2025
$2.3M
Atypical Angiogenic Mimicry During Collective Lung Cancer InvasionR01CA236369 · NCI · EMORY UNIVERSITY · PI MARCUS, ADAM I. · 2019 to 2023
$1.8M
Deconstructing the collective invasion pack to define Myo10 functionR01CA250422 · NCI · EMORY UNIVERSITY · PI MARCUS, ADAM I. · 2020 to 2024
$1.8M
Deconstructing cellular heterogeneity and subpopulation cooperation in non-small cell lung cancer metastasisR50CA265345 · NCI · EMORY UNIVERSITY · PI MOUW, JANNA K · 2021 to 2025
$720k
NCI NIH HHS P30 CA138292NCI NIH HHS R01 CA236369NCI NIH HHS R01 CA247367NCI NIH HHS R01 CA250422NCI NIH HHS R50 CA265345
6 · The paper itself

Abstract

Numerous techniques have been employed to deconstruct the heterogeneity observed in normal and diseased cellular populations, including single cell RNA sequencing,

Identifiers

PMID36909653
PMCPMC10002729
OpenAlexW4323050529

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.