ArticleRegenerative biomaterials2023
Electrospun naringin-loaded microsphere/sucrose acetate isobutyrate system promotes macrophage polarization toward M2 and facilitates osteoporotic bone defect repair.
Article in Regenerative biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Osteomyelitis: Epidemiology, Classification, Pathophysiology, Clinical Features, Diagnosis, and Management.MedComm · 2026Review
- 4D-printed Fe3O4-PLLA scaffolds modulate osteoimmune microenvironment for oral bone repair.Materials today. Bio · 2026Article
- Copper-incorporated hydrogels loaded with curcumin microspheres for the repair of bone defects.Materials today. Bio · 2025Article
- Nano MgO loaded thermosensitive HPCH@HA hydrogel accelerates in situ bone repair through osteoimmunomodulation while enhancing angiogenesis and osteogenesis.Bioactive materials · 2025Article
- Microenvironment-responsive hydrogels for spatiotemporal delivery of epigallocatechin gallate and BMP-2 to promote osteoporotic bone defect repair.Materials today. Bio · 2025Article
- Revolutionizing osteoporosis management: the emerging role of immunotherapeutic and next-generation therapies.Inflammopharmacology · 2025Review
- Article
- Development of a mechanical adaptable, moisture retention capable, injectable and adhesive organohydrogel for nucleus pulposus repairing.Regenerative biomaterials · 2025Article
- A 3D-printed scaffold composed of Alg/HA/SIS for the treatment of diabetic bone defects.Journal of orthopaedic translation · 2024Article
- A strategy for mechanically integrating robust hydrogel-tissue hybrid to promote the anti-calcification and endothelialization of bioprosthetic heart valve.Regenerative biomaterials · 2024Article
- Fibrous topology promoted pBMP2-activated matrix on titanium implants boost osseointegration.Regenerative biomaterials · 2024Article
- [Preparation of berberine-naringin dual drug-loaded composite microspheres and evaluation of their antibacterial-osteogenic properties].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023Article
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Authors and funding
7 authors.
Funding
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Abstract
Repairing osteoporotic bone defects is still a major clinical challenge. Recent studies have revealed that immune response is also essential in osteogenesis. The intrinsic inflammatory response of the host, especially the M1/M2 polarization status and inflammatory secretory function of macrophages, can directly affect osteogenic differentiation. Therefore, in this study, an electrospun naringin-loaded microspheres/sucrose acetate isobutyrate (Ng-m-SAIB) system was constructed to investigate its effect on the polarization of macrophage and osteoporotic bone defects. The results of both
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