Evidence map›Paper›PMID 36911193›Full record

ArticleFrontiers in bioengineering and biotechnology2023

Long-term cultures of human pancreatic islets in self-assembling peptides hydrogels.

Amanda Marchini, Maria Gessica Ciulla, Barbara Antonioli, Alessandro Agnoli, Umberto Bovio, Virginia Visnoviz, Federico Bertuzzi, Fabrizio Gelain

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amanda MarchiniInstitute for Stem-Cell Biology, Regenerative Medicine and Innovative Therapies (ISBReMIT), IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.
Maria Gessica CiullaInstitute for Stem-Cell Biology, Regenerative Medicine and Innovative Therapies (ISBReMIT), IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.
Barbara AntonioliTissue Bank and Tissue Therapy Unit, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Alessandro AgnoliDepartment of Biotechnology and Bioscience, University of Milan-Bicocca, Milan, Italy.
Umberto BovioDepartment of Biotechnology and Bioscience, University of Milan-Bicocca, Milan, Italy.
Virginia VisnovizDepartment of Molecular Medicine, University of Pavia, Pavia, Italy.
Federico BertuzziDepartment of Diabetology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Fabrizio GelainInstitute for Stem-Cell Biology, Regenerative Medicine and Innovative Therapies (ISBReMIT), IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human pancreatic islets transplantation is an experimental therapeutic treatment for Type I Diabetes. Limited islets lifespan in culture remains the main drawback, due to the absence of native extracellular matrix as mechanical support after their enzymatic and mechanical isolation procedure. Extending the limited islets lifespan by creating a long-term

Indexed as

biomimetic nanomaterialhuman pancreatic isletsself-assembling peptidesthree-dimensional cell culturestype 1 diabetes mellitus

Identifiers

PMID36911193
PMCPMC9995881

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.